Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Pathogenesis and advances in immunotherapy for type 1 diabetes treatment. [PDF]
Biotechnol Rep (Amst)Linh TC, Dung NK.
europepmc +1 more source
Effects of Oltipraz on the Glycolipid Metabolism and the Nrf2/HO-1 Pathway in Type 2 Diabetic Mice
Yunfei Luo +10 more
openalex +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Translation, Cultural Adaptation, and Validation of the Arabic Version of the Type 1 Diabetes Distress Scale (T1-DDS) Among Adults with Type 1 Diabetes in Saudi Arabia. [PDF]
Healthcare (Basel)Alguwaihes AM, Alenezi S.
europepmc +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
The Rise and Rise of Type 1 and Type 2 Diabetes in Youth. [PDF]
Diabetes Metab Syndr ObesDeBoer MD.
europepmc +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
(Not) "just your nature". Diagnostic journeys of adults with neurofibromatosis type 1 in Poland. [PDF]
Front GenetKowal K, Domaradzki J.
europepmc +1 more source
Human Immunodeficiency Virus Type 1 Gag Polyprotein Modulates Membrane Physical Properties like a Surfactant: Potential Implications for Virus Assembly [PDF]
Zaret G. Denieva +5 more
openalex +1 more source