Results 71 to 80 of about 37,382,072 (281)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
BMC Medical Research MethodologyBackground Many statistical methods used in public health research, namely t-tests, ANOVA correlation and regression, rely on the assumption of normality. Violation of the normality assumption can severely lead to biased parameter estimates, reduced test
Asha Kamath +2 more
doaj +1 more source
Stability, instability, and error of the force-based quasicontinuum approximation [PDF]
, 2009 Due to their algorithmic simplicity and high accuracy, force-based model coupling techniques are popular tools in computational physics. For example, the force-based quasicontinuum (QCF) approximation is the only known pointwise consistent quasicontinuum
Luskin, Mitchell Barry +5 more
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
(In)accurate Intuition: Fast Reasoning in Decision Making
Journal of European Psychology Students, 2013 Dual-process theories postulate a distinction between fast, automatic, intuitive and error-prone (Type 1) versus slow, controlled, deliberate and analytic (Type 2) processes. When less time is available, performance is predicted to be based on low-effort
Michalina Andrzejewska +5 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
GMS Medizinische Informatik, Biometrie und Epidemiologie, 2018 Background: When assessing the benefit of an intervention, the study population (SP) may consist of a relevant target population (ZP) and a non-relevant population (nZP).
Beckmann, Lars +5 more
doaj +1 more source
Control of Type 1 and Type 2 Errors in Configural Frequency Analysis
Journal for Person-Oriented ResearchIn this article, standard configural frequency analysis (CFA) is compared with combinatorial Victor CFA with respect to Type I errors and power. Victor CFA is most important and suitable when phantom types or phantom antitypes are suspected to exist. These can emerge when types and antitypes contain cases from populations other than the sample under ...
Stefan Von Weber, Alexander Von Eye
openaire +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source