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Fimbriae reprogram host gene expression - Divergent effects of P and type 1 fimbriae. [PDF]

open access: yesPLoS Pathogens, 2019
Pathogens rely on a complex virulence gene repertoire to successfully attack their hosts. We were therefore surprised to find that a single fimbrial gene reconstitution can return the virulence-attenuated commensal strain Escherichia coli 83972 to ...
Ines Ambite   +10 more
doaj   +7 more sources

Type 1 fimbriae-mediated collective protection against type 6 secretion system attacks [PDF]

open access: yesmBio
Bacterial competition may rely on secretion systems such as the type 6 secretion system (T6SS), which punctures and releases toxic molecules into neighboring cells.
Margot Marie Dessartine   +4 more
doaj   +6 more sources

What Flips the Switch? Signals and Stress Regulating Extraintestinal Pathogenic Escherichia coli Type 1 Fimbriae (Pili) [PDF]

open access: yesMicroorganisms, 2021
Pathogens are exposed to a multitude of harmful conditions imposed by the environment of the host. Bacterial responses against these stresses are pivotal for successful host colonization and pathogenesis. In the case of many E.
Hicham Bessaiah   +3 more
doaj   +3 more sources

The osmoregulated metabolism of trehalose contributes to production of type 1 fimbriae and bladder colonization by extraintestinal Escherichia coli strain BEN2908 [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology
In Escherichia coli, the disaccharide trehalose can be metabolized as a carbon source or be accumulated as an osmoprotectant under osmotic stress. In hypertonic environments, E. coli accumulates trehalose in the cell by synthesis from glucose mediated by
Vivian Souza Klemberg   +8 more
doaj   +3 more sources

Distinct mutations led to inactivation of type 1 fimbriae expression in Shigella spp. [PDF]

open access: yesPLoS ONE, 2015
Shigella spp. are responsible for bacillary dysentery in humans. The acquisition or the modification of the virulence plasmid encoding factors promoting entry of bacteria into and dissemination within epithelial cells was a critical step in the evolution
Verónica Bravo   +4 more
doaj   +7 more sources

Adhesion of Escherichia Coli to Nanostructured Surfaces and the Role of Type 1 Fimbriae [PDF]

open access: yesNanomaterials, 2020
Bacterial fimbriae are an important virulence factor mediating adhesion to both biotic and abiotic surfaces and facilitating biofilm formation. The expression of type 1 fimbriae of Escherichia coli is a key virulence factor for urinary tract infections ...
Pawel Kallas   +6 more
doaj   +3 more sources

yqhG Contributes to Oxidative Stress Resistance and Virulence of Uropathogenic Escherichia coli and Identification of Other Genes Altering Expression of Type 1 Fimbriae [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2019
Urinary tract infections (UTIs) are common bacterial infections and the vast majority of UTIs are caused by extraintestinal pathogenic Escherichia coli (ExPEC) strains referred to as uropathogenic E. coli (UPEC).
Hicham Bessaiah   +9 more
doaj   +3 more sources

Strain and host-cell dependent role of type-1 fimbriae in the adherence phenotype of super-shed Escherichia coli O157:H7 [PDF]

open access: yesInternational Journal of Medical Microbiology, 2021
Super-shed (SS) Escherichia coli O157 (E. coli O157) demonstrate a strong, aggregative, locus of enterocyte effacement (LEE)-independent adherence phenotype on bovine recto-anal junction squamous epithelial (RSE) cells, and harbor polymorphisms in non ...
Robab Katani   +10 more
doaj   +3 more sources

Pre-Growth Culture Conditions Affect Type 1 Fimbriae-Dependent Adhesion of Salmonella. [PDF]

open access: yesInt J Mol Sci, 2020
Among various fimbrial structures used by Salmonella enterica to colonize host tissues, type 1 fimbriae (T1F) are among the most extensively studied. Although some experiments have shown the importance of T1F in the initial stages of Salmonella infection,
Klasa B, Kędzierska AE, Grzymajło K.
europepmc   +5 more sources

Arginine within a specific motif near the N‐terminal of FimY is critical for the maximal production of type 1 fimbriae in Salmonella enterica serovar Typhimurium [PDF]

open access: yesMicrobiologyOpen, 2019
An important Salmonella serovar for both human and animals Salmonella Typhimurium possesses 13 gene clusters that have the potential to produce fimbrial structure, among which the type 1 fimbriae with the binding specificity to mannose residue is the ...
Nan‐Ling Kuan, Kuang‐Sheng Yeh
doaj   +3 more sources

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