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1999
Type 2 diabetes mellitus is a disease characterized by both abnormalities in insulin secretion and target-tissue resistance to the actions of insulin. Therefore, it is not surprising that replacement therapy with insulin alone is not sufficient to control blood glucose and many of the other metabolic abnormalities in patients with type 2 diabetes ...
Rubin Bressler, David Johnson
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Type 2 diabetes mellitus is a disease characterized by both abnormalities in insulin secretion and target-tissue resistance to the actions of insulin. Therefore, it is not surprising that replacement therapy with insulin alone is not sufficient to control blood glucose and many of the other metabolic abnormalities in patients with type 2 diabetes ...
Rubin Bressler, David Johnson
openaire +2 more sources
Liraglutide for type 2 diabetes mellitus
Expert Opinion on Biological Therapy, 2011Prevalence of type 2 diabetes mellitus (T2DM) is increasing. Management of this condition and minimizing the cardiovascular risks associated with it poses a significant burden on healthcare resources across the world. Currently available therapeutic agents are effective in glycemic management; however, the majority of these are associated with ...
Kela, R, Khunti, K, Davies, MJ
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Type 2 diabetes mellitus in older adults: clinical considerations and management
Nature Reviews Endocrinology, 2021S. Bellary +3 more
semanticscholar +1 more source
Hyperuricaemia and type 2 diabetes mellitus
Clinical and Experimental Pharmacology and Physiology, 2018SummaryChoi et al reported the effect of hyperuricaemia on the new‐onset type 2 diabetes mellitus (T2DM). I present three queries. (i) Insulin is considered to stimulate uric acid reabsorption via specific transporter and the effect of hyperuricaemia on the new‐onset T2DM should be evaluated by considering insulin resistance. (ii) There is a limitation
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Genes and Type 2 Diabetes Mellitus
Archives of Medical Research, 2005Type 2 diabetes (T2DM) comprises a group of entities with different genetic causes. In most patients, T2DM results from alterations of various genes, each having a partial and additive effect. The inheritance pattern is thus complex, and environmental factors play an important role in favoring or delaying the expression of the disease.
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Pancreatic β-cells in type 1 and type 2 diabetes mellitus: different pathways to failure
Nature Reviews Endocrinology, 2020D. Eizirik, L. Pasquali, M. Cnop
semanticscholar +1 more source
Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis
The Lancet, 2009L. Bellamy +3 more
semanticscholar +1 more source
Prevention of Type 2 Diabetes Mellitus
2009Both epidemiology and pathophysiology of type 2 diabetes are discussed in detail elsewhere in this textbook ( Chapters 8 and 13). For the purpose of this chapter, a brief summary of these topics is provided.
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An overview of real‐world data sources for oncology and considerations for research
Ca-A Cancer Journal for Clinicians, 2022Lynne Penberthy +2 more
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