Results 41 to 50 of about 119,720,646 (296)

PARTIAL THROMBOSIS OF THE FALSE LUMEN IN PATIENTS WITH ACUTE TYPE B AORTIC DISSECTION

, 2007
BACKGROUND: Patency or thrombosis of the false lumen in type B acute aortic dissection has been found to predict outcomes. The prognostic implications of partial thrombosis of the false lumen have not yet been elucidated.
FROEHLICH J, ISSELBACHER EM, FATTORI, ROSSELLA, EVANGELISTA A, LLOVET A, HUTCHISON S, SMITH DE, SUNDT T, JANUZZI JL JR, EAGLE KA, DISTANTE, ALESSANDRO, MEINHARDT G, MYRMEL T, Distante A, COOPER JV, SUZUKI T, BECKMAN J, NIENABER CA, FATTORI R, TSAI TT, INTERNATIONAL REGISTRY OF ACUTE AORTIC DISSECTION   +20 more
core   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Simple risk models to predict surgical mortality in acute type A aortic dissection: the International Registry of Acute Aortic Dissection score

, 2007
Background: Surgical mortality for acute type A aortic dissection is frequently related to preoperative clinical conditions. We report a predictive score to identify risk of death that may be helpful to assist surgeons who are considering whether to ...
Oh JK, Deeb MG, Isselbacher EM, Tsai T, Eagle KA, Fang J, Sechtem U, Fattori R, Smith D, FATTORI, ROSSELLA, Nienaber CA, Myrmel T, De Vincentiis C, Rampoldi V, Cooper JV, International Registry of Acute Aortic Dissection Investigators, Sangiorgi GM, Raghupathy A, Fang JM, Sundt TM 3rd, Sundt TM, Trimarchi S, Bossone E   +22 more
core   +2 more sources

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

Management of acute type B aortic dissection [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2013
Acute type B aortic dissection (identified within 2 weeks of symptom onset), as described using the Stanford classification, involves the aorta distal to the left subclavian artery and accounts for 25%-40% of all aortic dissections. The traditional treatment paradigm of medical management for uncomplicated acute type B dissection and open surgical ...
Hughes, G. Chad, Andersen, Nicholas D., McCann, Richard L.   +2 more
openaire   +2 more sources

Advanced Flexible Robotic Systems for the Early Diagnosis and Treatment of Cancer and Cardiovascular Diseases

Advanced Robotics Research, EarlyView.
Flexible surgical robots are advancing minimally invasive interventions for cardiovascular diseases and cancer by enabling precise navigation through complex, submillimeter anatomical pathways. This review highlights recent innovations in actuation, bio‐integrated sensing, AI‐assisted control, and friction‐reduction technologies, discusses current ...
Hermione Truong, Chi Cong Nguyen, Hannah Thuy Truong, Kefan Zhu, Adrienne Ji, James Davies, Emanuele Nicotra, Bibhu Sharma, Jingjing Wan, Patrick Pruscino, Shing Wai Wong, Hoang‐Phuong Phan, Phuoc Thien Phan, Nigel H. Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang, Bangheng Liu, Yulei Mu, Huiqun Zhou, Liang Ma, Chenjie Xu, Dong‐An Wang   +6 more
wiley   +1 more source

Management of acute type A aortic dissection with acute lower extremities malperfusion

Journal of Cardiothoracic Surgery, 2019
Background Acute type A aortic dissection complicated by malperfusion is a life – threatening emergency. The optimal management strategy for malperfusion remains controversial.
Dong Hoon Kang, Jong Woo Kim, Sung Hwan Kim, Seong Ho Moon, Jun Ho Yang, Jae Jun Jung, Hyun Oh. Park, Jun Young Choi, In Seok Jang, Chung Eun Lee, Jong Duk Kim, Joung Hun Byun   +11 more
doaj   +1 more source

Systolic anterior motion of the mitral valve associated with acute type A aortic dissection: a case report describing one-step surgery of ascending aortic replacement and interventricular septal myectomy

Surgical Case Reports, 2021
Background Systolic anterior motion of the mitral valve associated with acute type A aortic dissection is rare in daily clinical practice. The prevention of systolic anterior motion is important, because once it occurs, the hemodynamics may become ...
Naoki Yamamoto, Koji Onoda
doaj   +1 more source

Central cannulation for type A acute aortic dissection [PDF]

Interactive Cardiovascular and Thoracic Surgery, 2003
We present a simple new method for establishing cardiopulmonary bypass to treat type A acute aortic dissection. Antegrade blood flow in the true lumen is theoretically best to prevent malperfusion and retrograde embolization. Central cannulation can be performed in the true lumen of the dissected ascending aorta using an ultrasonographically guided ...
Tomoyuki, Yamada, Ario, Yamazato
openaire   +2 more sources