Results 141 to 150 of about 47,460 (264)

SURGELLA: A Scoping Review of Impella‐Assisted Hemodynamic Support in High‐Risk Non‐Cardiac Surgery

Artificial Organs, EarlyView.
In selected patients with severe LV dysfunction, Impella‐supported non‐cardiac surgery may provide a temporary hemodynamic bridge to otherwise prohibitive procedures. Published evidence remains limited to a small number of highly selected cases, supporting technical feasibility rather than comparative benefit or generalizable safety.
Hussein Elghazaly, Mohammed Allaf, Areeb Mian, Hanad Ahmed, Alex Gordon‐Weeks, Alexander Tindale, Vasileios Panoulas   +6 more
wiley   +1 more source

Predictive Value of D-Dimer to Albumin Ratio for Outcome in Acute Type A Aortic Dissection Patients. [PDF]

J Clin Hypertens (Greenwich)
Lin A, Peng Y, Shao J, Chen L, Lin Y.
europepmc   +1 more source

Standardized Reporting of Cardiac Magnetic Resonance Examinations in Children With Cardiac Diseases and Adults With Congenital Heart Disease: A Scientific Statement From the Association for European Pediatric and Congenital Cardiology (AEPC) and the International Society for Magnetic Resonance in Medicine (ISMRM)

Journal of Magnetic Resonance Imaging, EarlyView.
Francesca Raimondi, Inga Voges, Lamia Ait‐Ali, Sonya Babu‐Narayan, Rene Botnar, Barbara Burkhardt, Adrienne Campbell‐Washburn, Dominik Daniel Gabbert, Georg Hansmann, Willem A. Helbing, Hasan Hosan, Sylvia Krupickova, Heiner Latus, Duarte Martins, Colin McMahon, Christian Meierhofer, Vivek Muthurangu, Tiina Ojala, Pim van Ooij, Claudia Prieto, Milan Prsa, Kuberan Pushparajah, José F. Rodríguez Palomares, Samir Sarikouch, Lars Grosse‐Wortman, F. Gerald Greil, Heynric Grotenhuis   +26 more
wiley   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source

The aortic window: a temporal framework for acute type A aortic dissection. [PDF]

Ann Cardiothorac Surg
Holia F, Oo AY, Bicknell CD, Athanasiou T, Fowler C, Nienaber CA, Cooper G, Göncz E, Elefteriades JA, Schäfers HJ.   +9 more
europepmc   +1 more source

Inhibition of late sodium current prevents pathological hyperactivation of calcium/calmodulin‐dependent protein kinase IIδ in a murine model of acute doxorubicin‐related cardiotoxicity

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Doxorubicin (DOX) is a highly effective anthracycline, whose clinical application for cancer is limited by cardiotoxicity. The mechanisms underlying doxorubicin‐induced toxic cardiomyopathy (DICM) involve electrophysiological remodelling with intracellular Na+ overload because of increased late INa and hyperactivation of
Anna‐Lena Feder, Anna‐Maria Pfützenreuter, Lea Maria Funke, Maria Johanna Baier, Daniel Tarnowski, Laura Stengel, Lars Siegfried Maier, Can Martin Sag   +7 more
wiley   +1 more source

First Latin American Experience With a Hybrid Dissection Stent in Type A Aortic Dissection. [PDF]

JACC Case Rep
Choquehuanca-Bedoya HS, Fernández-Quiroz JM, Barrantes-Alarcón C, Tsuha-Alvarado LA, Ramos-Isidro RE.   +4 more
europepmc   +1 more source

Targeting PCSK9 in Vascular Smooth Muscle Cells: An Effective Strategy to Suppress Ferroptosis and Attenuate Abdominal Aortic Aneurysm Progression

Cell Proliferation, EarlyView.
PCSK9 aggravates AAA by promoting ferroptosis in VSMCs. In the pathological AAA environment, PCSK9 upregulation triggers ferritinophagy‐dependent degradation of FTH1, leading to Fe2+ release, triggering lipid peroxidation and ferroptosis, exacerbating AAA.
Mengdie Xia, Man Li, Yanyu Chen, Jialin Chen, Yuting Cui, Xi‐Long Zheng, Jing Yang, Bingzhao Li, Xiaofeng Ma, Miao Liu, Gang Fan, Juan Peng, Xiaoyan Dai, Zhihan Tang   +13 more
wiley   +1 more source

A dynamic recovery failure index after acute type A aortic dissection surgery. [PDF]

Ann Med
Yuan S, Li L, Wei M, Wang Z, Zhang R, Ma Y, Wang Z, Tao C, Zhou Z, Liu X, Lu Y, An Q, Liu F, Fu G, Yang R, Li P.   +15 more
europepmc   +1 more source

MD‐1 Deficiency Mitigates Atherosclerosis by Inhibiting NLRP3 Inflammasome Activation via cGAS‐STING Dependent Pathway in Macrophages

Cell Proliferation, EarlyView.
MD‐1 is induced and activated in macrophages. The activated MD‐1 subsequently promotes the cGAS‐STING‐TBK1‐IRF3 signalling pathway to activate the NLRP3 inflammasome, and subsequently increases pro‐inflammatory macrophage polarisation and decreases plaque stability to accelerate the development of atherosclerosis.
Fang Zhao, Zhili Jin, Zhiwei Cai, Quan Zhang, Tao He, Xiangjie Kong, Ming Chen, Zhibing Lu, Xiaorong Hu, Wen‐Lin Cheng   +9 more
wiley   +1 more source