Results 91 to 100 of about 1,995,270 (268)
Impact of an electric field on P-type ATPases [PDF]
, 2008 P-type ATPases are membrane proteins acting as ion pumps that drive an active transport of cations across the membrane against a concentration gradient. The required energy for the ion transport is provided by binding and hydrolysis of ATP.
Weidemüller, Christian, Hauser, Karin
core +1 more source
iScience, 2019 Summary: Protein kinase B/AKT is a highly connected protein involved in a range of signaling pathways. Although it is known to regulate several proteins in the apoptotic pathway, its system-level effects remain poorly understood.
Matthew W. Anderson +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
An Exploration of Senior High School Student Learning in Biology in Taiwan [PDF]
, 2006 This thesis explores senior high school student learning in biology in Taiwan. The Confucian-heritage culture and beliefs associated with high stakes examinations influences the learning context in biology.
Lu, Tan-Ni
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Metabolomic associations of impaired awareness of hypoglycaemia in type 1 diabetes
Scientific ReportsThis study investigates impaired awareness of hypoglycaemia (IAH), a complication of insulin therapy affecting 20–40% of individuals with type 1 diabetes.
R. D. M. Varkevisser +7 more
doaj +1 more source
The emerging role of targeting cancer metabolism for cancer therapy
Tumor Biology, 2020 Glucose, as the main consuming nutrient of the body, faces different destinies in cancer cells. Glycolysis, oxidative phosphorylation, and pentose phosphate pathways produce different glucose-derived metabolites and thus affect cells’ bioenergetics ...
Pegah Farhadi +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Reproductive biology of varroa mites in colonies of Africanized honey bees [PDF]
, 2009 We investigated the reproductive biology of V. destructor in Africanized honeybees (AHB) in Central American conditions, specifically in Costa Rica. Attention was paid to mite fertility and production of viable female mites in worker and drone brood ...
Behavioral Biology +2 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Nitric oxide synthase in skeletal muscle fibres of patients with type 2 diabetes [PDF]
, 2012 Muscle-derived nitric oxide (NO) mediates fundamental physiological actions on skeletal muscle including glucose uptake into muscle cells. Recently, we have shown that the altered glucose metabolism in skeletal muscle of patients with type 2 diabetes ...
Karla Punkt +5 more
core +1 more source