Results 41 to 50 of about 30,607,253 (282)
Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids
Pediatric Blood &Cancer, EarlyView.ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz +12 more
wiley +1 more source
C-type lectins and phagocytosis
Immunobiology, 2009 To recognise and respond to pathogens, germ-line encoded pattern recognition receptors (PRRs) bind to conserved microbial structures and activate host defence systems, including microbial uptake by phagocytosis. Phagocytosis is a complex process that is instrumental in the control of extracellular pathogens, and this activity is mediated by several ...
Kerrigan, Ann, Brown, Gordon D
openaire +3 more sources
Hepatitis C virus and HIV type 1 co-infection
Infectious Disease Reports, 2013 Around 33 million people worldwide are living with Human Immunodeficiency Virus (HIV) infection, and approximately 20-30% of HIV-infected individuals are also infected with Hepatitis C virus (HCV). The main form of HCV transmission is via the blood borne
Priyanka Gupta
doaj +1 more source
The Role of the CXCL12/CXCR4/CXCR7 Chemokine Axis in Cancer
Frontiers in Pharmacology, 2020 Chemokines are a family of small, secreted cytokines which regulate a variety of cell functions. The C-X-C motif chemokine ligand 12 (CXCL12) binds to C-X-C chemokine receptor type 4 (CXCR4) and C-X-C chemokine receptor type 7 (CXCR7). The interaction of
Yi Shi, David J. Riese, Jianzhong Shen
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben +4 more
wiley +1 more source
Acta Crystallographica Section E, 2009 The title compound, neodymium sesquiselenide, is isotypic with the other known rare-earth metal(III) selenides M2Se3 (M = La–Pr and Sm–Lu) with the cubic C-type structure. It adopts a cation-defective Th3P4-type arrangement with close
doaj +1 more source
THE NATURE OF THE TYPE C SEMI-REGULAR VARIABLES
Odessa Astronomical Publications, 2017 The type C semi-regular (SRC) variables are M-type supergiants like Betelgeuse that undergo regular periodic brightness fluctuations superposed upon seemingly irregular trends.
D. G. Turner
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk +10 more
wiley +1 more source
IUCrDataThe title compound, diytterbium enneaoxidotritellurate(IV), was obtained in its C-type crystal structure from the binary oxides at 1073 K using a CsCl flux. It crystallizes isotypically with C-type Tm2Te3O9 and Lu2Te3O9, closing this gap of knowledge.
Patrick Höss +4 more
doaj +1 more source
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source