A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
wiley +1 more source
Decline by design: Assessing decline policies as a decarbonisation strategy under the Paris Agreement. [PDF]
Trencher G +4 more
europepmc +1 more source
Pool-Type LMFBR Plant 1000 MWe Phase A design. Part IV. Appendix, final report
openalex +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Assessing rapid response mobile laboratory (RRML) capacities in Europe and Africa to improve One Health disease surveillance activities and pandemic preparedness across two continents. [PDF]
Trojnacki A +26 more
europepmc +1 more source
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
Design of novel plate for fixation of anterior pelvic ring injury: a digital anatomy study and finite element analysis. [PDF]
Yu K, Gao S, Wu M.
europepmc +1 more source
Nonlinear Feedback Design for Fixed-Time Stabilization of Linear Control Systems
A. Polyakov
semanticscholar +1 more source

