Results 181 to 190 of about 25,160 (214)

Incidence and Predictors of Immune‐Related Hypothyroidism Under Pembrolizumab Across Gynecologic Malignancies and Melanoma: A Real‐World Cohort Study

International Journal of Cancer, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) frequently cause thyroid immune‐related adverse events (irAEs). Permanent hypothyroidism, the clinically most relevant phenotype, requires lifelong hormone replacement. We investigated its incidence, course, risk factors, and prognostic relevance under pembrolizumab.
Freya Koffka, Johann Kornowski, Elena Laakmann, Barbara Schmalfeldt, Tim Zell, Glenn Geidel, Christoffer Gebhardt, Pia Roser, Volkmar Müller, Julian Kött   +9 more
wiley   +1 more source

The Prognostic Value of the Endothelial Activation and Stress Index in Stable Patients with Idiopathic Pulmonary Arterial Hypertension. [PDF]

J Clin Med
Karauzum K, Yilmaz I, Kandemir AS, Rahimipour H.   +3 more
europepmc   +1 more source

Perioperative Avelumab and Chemotherapy for Gastroesophageal Adenocarcinoma: Long‐Term Survival Outcomes

International Journal of Cancer, EarlyView.
ABSTRACT Long‐term survival data for patients with locally advanced gastro‐esophageal adenocarcinoma (GEA) treated with neoadjuvant chemoimmunotherapy are lacking. We describe the long‐term disease‐free survival (DFS) and overall survival (OS) outcomes of such patients treated with a novel neoadjuvant chemoimmunotherapy regimen, aDCF (avelumab with ...
Thierry Alcindor, James Tankel, Pierre‐Olivier Fiset, Mehrnoush Dehghani, Nicholas Bertos, Carmen Mueller, Jonathan Cools‐Lartigue, Sophie Camilleri‐Broet, Lorenzo Ferri   +8 more
wiley   +1 more source

Reed-Sternberg cells express CD161 and lectin-like transcript 1 in Hodgkin lymphoma. [PDF]

Front Med (Lausanne)
Rjoop A, Al-Samama'h R, Al-Eitan L.
europepmc   +1 more source

Concomitant Use of Proton Pump Inhibitors and Survival Outcomes in Patients Receiving Adjuvant Chemotherapy for Stage III Colon Cancer

International Journal of Cancer, EarlyView.
ABSTRACT Proton pump inhibitors (PPIs) are commonly prescribed in patients with cancer. Prior studies suggest concomitant PPI use may reduce the efficacy of oral capecitabine through impaired absorption, with no interaction expected with intravenous 5‐fluorouracil (5‐FU). Using the Australian Comprehensive Cancer Outcomes and Research Database (ACCORD),
Matthew Loft, Vinoja Ganeshanathan, Rachel Wong, Shehara Mendis, Matthew Croxford, Ian T. Jones, Grace Gard, Sue‐Anne McLachlan, Jeanne Tie, Lucy Gately, Peter Gibbs   +10 more
wiley   +1 more source

Teclistamab versus lenalidomide-dexamethasone in high-risk smoldering multiple myeloma: a randomized phase 2 trial. [PDF]

Nat Med
Nadeem O, Cordas Dos Santos DM, Magidson S, Matous J, Medvedova E, O'Donnell E, Redd RA, Liu Y, Midha S, Sperling AS, Arters F, Davie C, Ricciardi C, Toenges R, Bidikian N, Hussein S, Alberge JB, Kim S, Pantano-Rubino L, Corrado F, Ashton H, Addonizio D, Mohamed S, Sturtevant A, Marto M, Bergeron A, Malfona F, Panaro K, Richardson PG, Ritz J, Trippa L, Ghobrial IM.   +31 more
europepmc   +1 more source

Risk factors for intrapartum stillbirth and the survival probabilities of fetuses among pregnant women with complications: Secondary analysis of data from a multicenter prospective cohort study in India

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To identify the risk factors for intrapartum stillbirth and examine whether these are different from that of antepartum stillbirth, and investigate the survival probabilities of fetuses by gestational age in high‐risk pregnancies. Methods We conducted a secondary data analysis of a hospital‐based cohort study from India, including ...
Yebeen Ysabelle Boo, Saswati S. Choudhury, Farzana Zahir, Gitanjali Deka, Amrit K. Bora, Shakuntala Chhabra, Pramod Kumar, Pranabika Mahanta, Bina Minz, Anjali Rani, Sereesha Rao, Indrani Roy, Carolin Solomi V., Ashok Verma, Swapna Kakoty, Omesh Kumar Bharti, Rupanjali Deka, Charles Opondo, Tuck Seng Cheng, Jennifer J. Kurinczuk, Manisha Nair, on behalf of the MaatHRI collaborators   +21 more
wiley   +1 more source

Contrasting molecular and pharmacodynamic signatures of response and resistance to sequential bortezomib and temozolomide in recurrent IDH-wildtype glioblastoma and grade 4 IDH-mutant astrocytoma: an exploratory interim analysis of NCT03643549 phase IB/II trial. [PDF]

Biomark Res
Goplen D, Rahman MA, Brekke J, Waha A, Oltedal L, Haasz J, Kumar S, Birkeland E, Selheim F, Lie SA, Chekenya M.   +10 more
europepmc   +1 more source

Censored-Data-Aware Screening of Hazardous Metal(loid)s in Wild Mushrooms from Urban and Peri-Urban Green Spaces: Multielement Fingerprints and Adult Exposure Assessment. [PDF]

J Xenobiot
Peña-Fernández A, Lobo MC, Peña Fernández MÁ, Torrado Durán G, Evans MD, Sgamma T, Cámara-Pastor T, Jagdev GS.   +7 more
europepmc   +1 more source

Circulating matrix GLA protein during puberty in healthy and central precocious puberty children. [PDF]

Endocr Connect
Damholt MB, Holmboe SA, Petersen JH, Blomberg Jensen M, Juul A, Juel Mortensen L.   +5 more
europepmc   +1 more source