SIEVEseq: unified differential expression, variability, and skewness analyses using RNA-Seq data. [PDF]
Li H, Khang TF.
europepmc +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Erratum: [Corrigendum] Angiotensin II type 2 receptor-interacting protein 3a suppresses proliferation, migration and invasion in tongue squamous cell carcinoma via the extracellular signal-regulated kinase-Snai2 pathway. [PDF]
Zhao T +5 more
europepmc +1 more source
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Negative controls and how to use them: a guidance paper. [PDF]
Bots SH +6 more
europepmc +1 more source
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court +3 more
wiley +1 more source
Evolutionary adaptations in iron capture via type II pyoverdine in XDR <i>Pseudomonas aeruginosa ST235</i>. [PDF]
Vatansever C +11 more
europepmc +1 more source
Visualizing type II error in normality tests
This is an Accepted Manuscript of an article published by Taylor & Francis in “Visualizing type II error in normality tests” on 19th January 2017, available online: http://www.tandfonline.com/doi/full/10.1080/00031305.2016.1278035A Skewed Exponential ...
Marco Almagro, Lluís +2 more
core
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Simulation-based approach with an adaptive Type-II hybrid progressive censoring scheme to study the coefficient of variation of the weighted exponential distribution. [PDF]
Aljohani HM +5 more
europepmc +1 more source

