Results 121 to 130 of about 36,361 (349)
A Drosophila model of prion disease and its metabolic changes in the brain
Animal Models and Experimental Medicine, EarlyView.We developed a Drosophila model for prion disease, and flies were capable of expressing the hamster prion protein (HaPrP) under the control of the GAL4/UAS system. The model exhibited some characteristics of the disease in mammals and displayed alterations in protein, sphingolipid, and carbohydrate metabolism. Preliminary applications have demonstrated
Dongdong Wang +14 more
wiley +1 more source
Eye-tracking Study of Reading Speed from LCD Displays: Influence of Type Style and Type Size
Journal of Eye Movement Research, 2015 Increasing amounts of text are read from various types of screens. The shape and the size of a typeface determine the legibility of texts. The aim of this study was to investigate the legibility of different typefaces displayed on LCD screens.
Gregor Franken +2 more
doaj +1 more source
Capturing tacit knowledge: Documenting and understanding recent methodological innovation used in Design Doctorates in order to inform Postgraduate training provision [PDF]
, 2009 This paper presents a preliminary review of recent Design PhDs that identify and analyse the methodological innovation that is occurring in the field, in order to inform future provision of research training for Design PhDs. Six recently completed Design
Yee, Joyce
core
Animal Models and Experimental Medicine, EarlyView.Amantadine (AMA) regulates neurocyte apoptosis and inhibits neurocyte inflammation to prevent maternal immune activation (MIA) from affecting offspring behavior. Abstract Background Maternal viral infection during pregnancy can lead to maternal immune activation (MIA), increasing the risk of neurodevelopmental disorders in offspring.
Jianfei Wu +8 more
wiley +1 more source
Annals of Neurology, EarlyView.Objectives Prospective studies demonstrated that essential tremor is a risk factor for Parkinson's disease. Identifying clinical markers for conversion from essential tremor to essential tremor‐Parkinson's disease would be of considerable value. Rest tremor can be present in advanced essential tremor and may be a harbinger of conversion. We examined (1)
Elan D. Louis +3 more
wiley +1 more source
How companies use typeface design to engage consumers in charitable activities
Psychology & Marketing, 2022 X. Chu +3 more
semanticscholar +1 more source
Arthritis &Rheumatology, EarlyView.Objective Rheumatoid arthritis (RA)–associated anticitrullinated protein antibodies (ACPAs) target various antigens by binding short citrulline amino acid motifs, resulting in heterogeneous ACPA profiles among patients. Here we analyzed ACPA patterns by recognized citrulline motifs in relation to the RA risk factors HLA‐DRB1 shared epitope (SE) alleles
Linda Mathsson Alm +18 more
wiley +1 more source
Word recognition and content comprehension of subtitles for television by deaf children
JoSTrans: The Journal of Specialised Translation, 2014 This project explores how deaf children read subtitles on television. The participants – recruited from years 3 to 6 of a mainstream school with a hearing impairment unit – were exposed to both broadcast and enhanced subtitles and their performances were
Soledad Zarate, Joseph Eliahoo
doaj +1 more source
Arthritis &Rheumatology, Accepted Article.Objective Keratinocyte‐derived interferon kappa (IFN‐κ) is chronically overexpressed in human non‐lesional systemic lupus erythematosus (SLE) skin. Recent evidence suggests that epidermal signals instruct the immune system in SLE, but whether epidermal IFN‐κ alone is sufficient to drive lupus phenotypes has not been investigated.
Benjamin Klein +14 more
wiley +1 more source