Results 111 to 120 of about 9,407,309 (241)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Psycho-neural reduction through functional sub-types [PDF]
The paper argues that a functional reduction of ordinary psychology to neuropsychology is possible by means of constructing fine-grained functional, mental sub-types that are coextensive with neuropsychological types.
Soom, Patrice +2 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Intersection Types and Denotational Semantics: An Extended Abstract (Invited Paper)
This is a short survey of the use of intersection types for reasoning in a finitary way about terms interpretations in various models of lambda ...
Ronchi Della Rocca, Simona
core +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Subtyping and Inheritance for Inductive Types [PDF]
Inheritance and subtyping are key features of object-oriented languages. We show that there are corresponding (or, more precisely, dual) notions for inductive or algebraic datatypes: there is a natural notion of subtyping for these types and an ...
Erik Poll, Poll, Erik
core
Dynamic abstract data types based on algebraic graph transformations
S.236-254The concept of dynamic abstract data types was recently proposed by two of the authors as a dynamic extension of the well-known concept of abstract data types, motivated by several recent approaches in the area of algebraic specifications ...
Löwe, M., Ehrig, H., Orejas, F.
core
Treatment of luminal HER2-negative breast cancer: opinion of experts
The discussion, dedicated to the treatment of luminal HER2-negative breast cancer stages II and III, was attended by doctors from St. Petersburg – Maria Leonidovna Makarkina, M.D., oncologist of the outpatient department of the N. P.
E. V. Artemeva, M. L. Makarkina
doaj +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source

