Results 111 to 120 of about 9,407,309 (241)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Psycho-neural reduction through functional sub-types [PDF]

open access: yes, 2009
The paper argues that a functional reduction of ordinary psychology to neuropsychology is possible by means of constructing fine-grained functional, mental sub-types that are coextensive with neuropsychological types.
Soom, Patrice   +2 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Intersection Types and Denotational Semantics: An Extended Abstract (Invited Paper)

open access: yes, 2018
This is a short survey of the use of intersection types for reasoning in a finitary way about terms interpretations in various models of lambda ...
Ronchi Della Rocca, Simona
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Subtyping and Inheritance for Inductive Types [PDF]

open access: yes, 1997
Inheritance and subtyping are key features of object-oriented languages. We show that there are corresponding (or, more precisely, dual) notions for inductive or algebraic datatypes: there is a natural notion of subtyping for these types and an ...
Erik Poll, Poll, Erik
core  

Dynamic abstract data types based on algebraic graph transformations

open access: yes, 2022
S.236-254The concept of dynamic abstract data types was recently proposed by two of the authors as a dynamic extension of the well-known concept of abstract data types, motivated by several recent approaches in the area of algebraic specifications ...
Löwe, M., Ehrig, H., Orejas, F.
core  

Treatment of luminal HER2-negative breast cancer: opinion of experts

open access: yesЛечащий Врач
The discussion, dedicated to the treatment of luminal HER2-negative breast cancer stages II and III, was attended by doctors from St. Petersburg – Maria Leonidovna Makarkina, M.D., oncologist of the outpatient department of the N. P.
E. V. Artemeva, M. L. Makarkina
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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