Results 91 to 100 of about 573,178 (272)

Consensus Formation and Change are Enhanced by Neutrality

open access: yesAdvanced Science, EarlyView.
Neutral agents are shown to enhance both the formation and overturning of consensus in collective decision‐making. A general mathematical model and experiments with locusts and humans reveal that neutrality enables robust consensus via simple interactions and accelerates consensus change by reducing effective population size.
Andrei Sontag   +3 more
wiley   +1 more source

On the role of budgeting in the delegated provision of public goods under asymmetric information [PDF]

open access: yes
The present paper investigates the neglected topic of budgeting rules for public bureaucracies performing governmental activities within predetermined budgets under rules governing expenditure levels and composition.
Krause, Günter
core  

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

open access: yesAdvanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija   +22 more
wiley   +1 more source

Health technology assessment and its role in the future development of the Indian healthcare sector

open access: yesPerspectives in Clinical Research, 2012
Public expenditure on healthcare in India is low by international comparison, and access to essential treatment pushes many uninsured citizens below the poverty line.
Bastian Hass   +4 more
doaj   +1 more source

Health Care Reform: Separating Insurance from Income Redistribution [PDF]

open access: yes
Most systems of health care financing in EU member states currently include elements of income redistribution. The paper analyzes the effects of shifting this kind of redistribution to the tax system and argues that this reform could create two types of ...
Andreas Haufler, Friedrich Breyer
core  

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

open access: yesAdvanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li   +23 more
wiley   +1 more source

Redistribution and Provision of Public Goods in an Economic Federation [PDF]

open access: yes
This paper concerns redistribution and provision of public goods in an economic federation with two levels of government: a local government in each locality and a central government for the economic federation as a whole. We assume that each locality is
Aronsson, Thomas, Blomquist, Sören
core   +1 more source

The demand for military expenditure in authoritarian regimes [PDF]

open access: yes, 2011
We investigate how the influence of the military differs across authoritarian regimes and verify whether there are actually systematic differences in military expenditures amongst different forms of dictatorships.
Bove, Vincenzo, Brauner, Jennifer
core  

Hepatocyte PIEZO1 Negatively Regulates Lipogenesis and Ameliorates MASLD by Sensing Membrane Tension and Activating AMPK

open access: yesAdvanced Science, EarlyView.
Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen   +14 more
wiley   +1 more source

Governing Interest Groups and Rent Dissipation [PDF]

open access: yes
In a contest group - specific public goods we consider the effect that managing an interest group has on the rent dissipation and the total expected payoffs of the contest.
Gil S. Epstein, Yosef Mealem
core  

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