Results 91 to 100 of about 3,785,022 (294)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Frequency and types of uterine anomalies during caesarean section

Journal of Obstetrics and Gynaecology, 2018
In this study all women undergoing caesarean section were included regardless of the indication. After the foetus and placenta were delivered, the uterus was examined for the presence or absence of congenital malformation through digital palpation of uterine cavity and direct inspection of the fundus.
Magdy A, Mohamed, Mohamed Y, AbdelRahman
openaire   +2 more sources

Multi-proxy evidence from the exposed strata at Okpekpe, Imiegba, and environs for nomenclature as Mamu Formation, Benin Flank, NW Anambra basin, Nigeria

Journal of Nigerian Society of Physical Sciences
Litho-sections along Okpekpe, Imiegba, and environs have been studied for their textural and microfossil contents to elucidate this recently exposed lithostratigraphic unit in the Benin Flank of the Anambra Basin.
Israel Aruoriwo Abiodun Etobro, Omabehere Innocent Ejeh   +1 more
doaj   +1 more source

Active FEL-Klystrons as Formers of Femto-Second Clusters of Electromagnetic Field. Description of the Models Based on “Ordinary” FEL Sections [PDF]

Журнал нано- та електронної фізики, 2010
The qualitative properties discussion of the Femto-second active cluster FEL-klystrons, which are designed on the basis of “ordinary” FEL sections, is performed. Theoretical models of two different types of such devices are proposed.
V.V. Kulish, A.V. Lysenko, A.Ju. Brusnik
doaj  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Dentinogenesis imperfecta type II: Ultrastructure of teeth in sagittal sections

Folia Histochemica et Cytobiologica, 2013
The morphological abnormalities of the teeth of patients affected by dentinogenesis imperfecta type 2 (DI-II) may underlie the difficulties with the clinical restoration of such teeth. We therefore performed a scanning electron microscopy (SEM) study of four permanent first mandibular molars of four DI-II patients with periapical pathosis.
Wieczorek, Aneta, Loster, Jolanta
openaire   +4 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

NIP omega-categorical structures: the rank 1 case

, 2020
We classify primitive, rank 1, omega-categorical structures having polynomially many types over finite sets. For a fixed number of 4-types, we show that there are only finitely many such structures and that all are built out of finitely many linear ...
Simon, Pierre
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source