Results 101 to 110 of about 3,785,022 (294)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Energy dependence of the 16O + 12C potential of interaction [PDF]

Ядерна фізика та енергетика, 2013
The 16O + 12C scattering data originating from various measurements in the energy range from 1 to 100 MeV/nucleon have been analyzed within optical model (OM).
O. A. Ponkratenko, V. V. Uleschenko, Yu. O. Shyrma   +2 more
doaj  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Comparison between Two Kinds of Online Educational Interventions on Knowledge-Attitude and Practice of Prosthodontists about the Role of Intra-Oral Appliances in Management of Obstructive Sleep Apnea

Journal of Sleep Sciences, 2022
Background and Objective: Obstructive sleep apnea (OSA) needs early detection and effective treatments to reduce the risk of its harmful consequences. The aim of this study was to assess the knowledge and practice of prosthodontists about OSA and oral ...
Somayeh Niakan, Somayeh Allahyari, Amirhossein Vakilli   +2 more
doaj  

Precision Calculations for Associated WH and ZH Production at Hadron Colliders

, 2003
Recently the next-to-next-to-leading order QCD corrections and the electroweak O(alpha) corrections to the Higgs-strahlung processes ppbar/pp -> WH/ZH + X have been calculated. Both types of corrections are of the order of 5-10%.
Brein, O., Ciccolini, M., Dittmaier, S., Djouadi, A., Harlander, R., Krämer, M.   +5 more
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Bajocian-Bathonian strata of the north-eastern regions of Western Siberia: geological structure, seismic stratigraphy, zoning by seismic sections types [PDF]

Нефтегазовая геология: Теория и практика
The paper presents data on the geological structure of the Malyshev and Leontyev Formations in the northeastern regions of Western Siberia. Based on a comprehensive analysis of the seismic wave pattern of the Jurassic interval of the section on a series ...
Borisov E.V., Shestakova N.I., Nekhaev A.Yu.   +2 more
doaj  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

On Sectional Curvature of Boggino-Damek-Ricci Type Spaces

Tokyo Journal of Mathematics, 2000
Let \(\{{\mathfrak n},( ,)_{\mathfrak n}\}\) be a 2-step nilpotent metric Lie algebra, \(z\) its center and \(v\) the orthogonal complement of \(z\). Let \(a=\mathbb{R} A\) be a one-dimensional real vector space. For \(k>0\) one defines an action \(f\) of \(a\) on \({\mathfrak n}\) by \(f(A)V=kV/2\), \(f(A)Z=kZ\), \(V\in v\), \(Z\in z\).
openaire   +3 more sources

The Welfare Economics of Moral Hazard [PDF]

This paper shows that, except in certain limiting cases, competitive equilibrium with moral hazard is constrained inefficient. The first section compares the competitive equilibrium and the constrained social optimum in a fairly general model, and ...
Joseph Stiglitz, Richard Arnott
core