Results 141 to 150 of about 709,899 (268)

Type III gastric neuroendocrine tumor - a case report

, 2020
Teodora SPATARU, Lucian Negreanu
openalex   +1 more source

Urokinase-type plasminogen activator (uPA) is critical for progression of tuberous sclerosis complex 2 (TSC2)-deficient tumors [PDF]

, 2017
Victoria Stepanova, К. В. Дергилев, Kelci R. Holman, Yelena Parfyonova, З. И. Цоколаева, Mimi Teter, Elena N. Atochina‐Vasserman, Alla Volgina, С. В. Зайцев, Shane P. Lewis, Fedor Zabozlaev, Kseniya Obraztsova, Vera P. Krymskaya, Douglas B. Cines   +13 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Evaluation of the diagnostic value of combined gastrointestinal endoscopy and serum CEA and CA19-9 levels in gastrointestinal tumor. [PDF]

Medicine (Baltimore)
Lin M, Xiang S, Zhang Y, Sun Y, Tan X.
europepmc   +1 more source

Traditional Chinese medicine as potential adjuvants for tumor vaccines: a review of types, mechanisms, and forms [PDF]

Yongjia Cui, Lejun Gong, Chang Lei, Wenping Lü, Shihua Zhao, Zhili Zhuo, Xiangyang Zhang   +6 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Large-scale generative tumor synthesis in computed tomography images for improving tumor recognition. [PDF]

Nat Commun
Wu L, Zhuang J, Zhou Y, He S, Ma J, Luo L, Wang X, Ni X, Zhong X, Wu M, Zhao Y, Duan X, Vardhanabhuti V, Rajpurkar P, Chen H.   +14 more
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Multi-platform analysis of the tumor immune microenvironment associated with breast cancer subtypes. [PDF]

Oncoimmunology
Torland LA, Geisler J, Azimzade Y, Frafjord A, Røed Nilsen H, Buer L, Lømo J, Garred Ø, Tahiri A, Lyngra M, Øynebråten I, Corthay A, Sahlberg K, Kristensen V, Tekpli X.   +14 more
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source