Results 201 to 210 of about 709,899 (268)

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Application of three-dimensional Superb micro-vascular imaging (3D-SMI) combined with quantitative blood flow analysis in the noninvasive diagnosis of renal tumors. [PDF]

Ultrasound J
Mao Y, Yu C, Wang T, Li F, Hou W, Wei X, Mu J.   +6 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Evaluation of the zinc-fingers and homeoboxes 3 as a potential biomarker for prognosis prediction in lung adenocarcinoma. [PDF]

Front Med (Lausanne)
You Y, Li W, Gao L, Li T, Zhang X, Luo X.   +5 more
europepmc   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Exploring the molecular function of LYPD3 from pan-cancer to lung cancer: based on bioinformatics and cellular experiments. [PDF]

Mamm Genome
Shi YX, Yan JH, Dai PH.
europepmc   +1 more source

Trop-2 mRNA expression distribution across multiple solid tumor types in TCGA.

Peiwen Kuo (251923), Emon Elboudwarej (697310), Marianna Zavodovskaya (17290653), Kai-Wen Lin (21094499), Chingwei V. Lee (21094502), Lauri Diehl (249647), Jilpa Patel (15176046), Sabeen Mekan (15176049), Juliane M. Jürgensmeier (14981891)   +8 more
openalex   +1 more source

Tumor-infiltrating microbes and therapy response: a new frontier in triple-negative breast cancer precision oncology. [PDF]

J Immunother Cancer
Marcho LM, Chakravarthy KB, Jhawar SR, Spakowicz DJ.   +3 more
europepmc   +1 more source

The Recycling Collagen Receptor uPARAP Is a Unique Mediator of Stromal Drug Delivery to Carcinoma Cells. [PDF]

Mol Cancer Ther
Nørregaard KS, Larsen IME, Jürgensen HJ, Blomquist MH, Çakilkaya P, Metrangolo V, Perlado AM, Krigslund O, Gårdsvoll H, Poulsen TT, Mumberg D, Santoni-Rugiu E, Engelholm LH, Behrendt N.   +13 more
europepmc   +1 more source