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Safety and Efficacy of a Typhoid Conjugate Vaccine in Malawian Children
Background Typhoid fever caused by multidrug-resistant H58 Salmonella Typhi is an increasing public-health threat in sub-Saharan Africa. We present phase 3 efficacy data from an African trial of a Vi-polysaccharide typhoid conjugate vaccine (Vi-TCV ...
James E Meiring +2 more
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International journal of numerical modelling, 2023
Typhoid fever poses a severe hazard to public health and affects at least 27 million people annually around the globe. It is significant to conceptualize the key factors of the transmission phenomena of this bacterial infection.
Rashid Jan +3 more
semanticscholar +1 more source
Typhoid fever poses a severe hazard to public health and affects at least 27 million people annually around the globe. It is significant to conceptualize the key factors of the transmission phenomena of this bacterial infection.
Rashid Jan +3 more
semanticscholar +1 more source
Sahel Medical Journal, 2001
Typhoid fever continues to be a major public health problem in developing countries with about 33 million cases per year. Protective efficacy of traditional acetone/phenol killed vaccines is similar to newer typhoid vaccines (Ty21A and Vi antigen vaccine) but side effects of these newer vaccines are considerably less.
A, Aggarwal, A K, Dutta
openaire +2 more sources
Typhoid fever continues to be a major public health problem in developing countries with about 33 million cases per year. Protective efficacy of traditional acetone/phenol killed vaccines is similar to newer typhoid vaccines (Ty21A and Vi antigen vaccine) but side effects of these newer vaccines are considerably less.
A, Aggarwal, A K, Dutta
openaire +2 more sources
Summary Background Salmonella enterica serovar Typhi (S Typhi) is responsible for an estimated 20 million infections and 200 000 deaths each year in resource poor regions of the world.
Celina Jin, Malick M Gibani, Maria Moore
exaly +2 more sources
Typhoid vaccines: WHO position paper, March 2018 - Recommendations.
Vaccine, 2019This article presented the World Health Organization's (WHO) recommendations on the use of Typhoid vaccines excerpted from the Typhoid vaccines: WHO position paper - March 2018 published in the Weekly Epidemiological Record (World Health Organization ...
World Health Organization
semanticscholar +1 more source
, 2021
Our study screen for S. Typhi present in the gallbladder of (2 0 0) patients suffering from GD along with 40 normal gallbladders, the samples were taken and diagnosed at the Al-Hussein teaching and Al-Amel hospitals, as well as the Noor Al Hussein and ...
Z. K. Hanan +3 more
semanticscholar +1 more source
Our study screen for S. Typhi present in the gallbladder of (2 0 0) patients suffering from GD along with 40 normal gallbladders, the samples were taken and diagnosed at the Al-Hussein teaching and Al-Amel hospitals, as well as the Noor Al Hussein and ...
Z. K. Hanan +3 more
semanticscholar +1 more source
Vaccine, 2021
BACKGROUND Enteric fever, caused by Salmonella Typhi and S. Paratyphi, is a cause of high morbidity and mortality among children in South Asia. Rising antimicrobial resistance presents an additional challenge.
Rabab Batool +7 more
semanticscholar +1 more source
BACKGROUND Enteric fever, caused by Salmonella Typhi and S. Paratyphi, is a cause of high morbidity and mortality among children in South Asia. Rising antimicrobial resistance presents an additional challenge.
Rabab Batool +7 more
semanticscholar +1 more source
Current Infectious Disease Reports, 2004
Typhoid fever is caused by infection with Salmonella enterica serovar Typhi. The completion of the genome sequence of two Salmonella enterica serovar Typhi isolates is leading to new insights into the biology of this pathogen. Approximately 16 million cases occur worldwide each year.
openaire +2 more sources
Typhoid fever is caused by infection with Salmonella enterica serovar Typhi. The completion of the genome sequence of two Salmonella enterica serovar Typhi isolates is leading to new insights into the biology of this pathogen. Approximately 16 million cases occur worldwide each year.
openaire +2 more sources
The Indian Journal of Pediatrics, 1984
Since the desired improvement in the sanitation and nealth facilities is not likely in most areas of the third world in the near future, the necessity for typhoid vaccination cannot be easily disputed. The mechanisms of immune response in typhoid, especially with regard to the local gut factors are poorly understood.
O P, Ghai, V K, Paul
openaire +2 more sources
Since the desired improvement in the sanitation and nealth facilities is not likely in most areas of the third world in the near future, the necessity for typhoid vaccination cannot be easily disputed. The mechanisms of immune response in typhoid, especially with regard to the local gut factors are poorly understood.
O P, Ghai, V K, Paul
openaire +2 more sources
The Lancet, 2015
Control of typhoid fever relies on clinical information, diagnosis, and an understanding for the epidemiology of the disease. Despite the breadth of work done so far, much is not known about the biology of this human-adapted bacterial pathogen and the complexity of the disease in endemic areas, especially those in Africa.
John, Wain +4 more
openaire +2 more sources
Control of typhoid fever relies on clinical information, diagnosis, and an understanding for the epidemiology of the disease. Despite the breadth of work done so far, much is not known about the biology of this human-adapted bacterial pathogen and the complexity of the disease in endemic areas, especially those in Africa.
John, Wain +4 more
openaire +2 more sources

