Results 61 to 70 of about 71,303 (143)

Over diagnosis of typhoid and malaria co-infection by health care workers in north central Nigeria: a cross-sectional study

open access: yesNigerian Journal of Medicine, 2020
Introduction: Typhoid and malaria are significant causes of morbidity and mortality, especially in sub-Saharan Africa. Typhoid and malaria co-infection may occur as superinfection or even simultaneous infections. However, it appears to be rather rare. It
N Y Shehu   +6 more
doaj   +1 more source

Water, Hygiene and Inequality: Keys to Understanding and Combating the Current Cholera Epidemic in the Democratic Republic of Congo—A Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aim The Democratic Republic of the Congo (DRC) is among the countries most affected by cholera in the world. Since the 1970s, endemic foci have persisted in the eastern lake provinces, where chronic armed conflict, massive population displacement, and extreme socioeconomic inequalities create particularly favorable conditions ...
Hermann Yokolo   +4 more
wiley   +1 more source

The YrbE phospholipid transporter of Salmonella enterica serovar Typhi regulates the expression of flagellin and influences motility, adhesion and induction of epithelial inflammatory responses

open access: yesGut Microbes, 2020
Salmonella enterica serovar Typhi is the etiologic agent of typhoid fever, a major public health problem in the developing world. Moving toward and adhering to the intestinal epithelium represents key initial steps of infection by S. Typhi.
Smriti Verma   +8 more
doaj   +1 more source

Pharmacy‐Based Immunization Delivery: A Comprehensive History and Current Challenges

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 6, June 2026.
ABSTRACT Pharmacists and their teams have a long history of involvement with vaccines. This paper describes the contributions of pharmacy‐based immunization delivery in the United States from the 1800's to date. Early activities centered around storage and distribution of antitoxins and vaccines. From the 1950s through the early 1990s, pharmacists were
Jean‐Venable R. Goode   +4 more
wiley   +1 more source

Guidelines for Essential Trauma Care: Second Edition (2026)

open access: yesWorld Journal of Surgery, Volume 50, Issue 6, Page 1409-1450, June 2026.
Injury is a major cause of death and disability globally, with the highest burden in low‐ and middle‐income countries (LMICs). Strengthening the organization and planning for trauma care (care of the injured) can improve care and lower mortality. In 2004, the International Association for Trauma Surgery and Intensive Care (IATSIC) and the World Health ...
Charles Mock   +41 more
wiley   +1 more source

Species‐Specific Optimisation and Environmental Regulation of Biofilm Formation in Enterobacter cloacae: Inhibitory Role of Glucose in Biofilm Development

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 3, June 2026.
This study demonstrates that mild salinity stress (1%–2% NaCl) significantly enhances biofilm formation in Enterobacter cloacae. Using a standardised 96‐well microtiter plate assay, we optimised in vitro biofilm quantification and classification, providing a reproducible framework for studying environmental and clinical biofilm development mechanisms ...
Srishti Singh   +6 more
wiley   +1 more source

Assessing Risk Thresholds in Controlled Human Infection Models (CHIM)

open access: yesBioethics, Volume 40, Issue 5, Page 519-529, June 2026.
ABSTRACT Controlled Human Infection Models (CHIMs) are a type of clinical trial involving deliberately exposing human volunteers to an infectious agent. Compared to studies of natural infection, CHIMs offers distinctive benefits, from the ability to study presymptomatic infection to a direct assessment of the efficacy of vaccines and therapeutics in a ...
Alexa Nord‐Bronzyk   +4 more
wiley   +1 more source

Typhoid Toxin of Salmonella enterica Induces ISG15 Responses Mediating Host Cell Survival and Counteracting Intracellular Infection

open access: yesMolecular Microbiology, Volume 125, Issue 6, Page 475-492, June 2026.
Toxigenic Salmonella enterica exocytose the typhoid toxin during infection causing host cell DNA damage, which activates a Type‐1 Interferon‐like response characterised by interferon‐stimulated gene 15 (ISG15) expression. ISG15 was required for host cell survival during Interferon responses and suppressed intracellular growth of Salmonella. Thus, ISG15
Daniel S. Stark   +11 more
wiley   +1 more source

Trends in typhoid fever during the COVID-19 pandemic in Pakistan

open access: yesJournal of Infection in Developing Countries
Introduction: Pakistan has been experiencing an extensively drug-resistant (XDR) outbreak of typhoid for some years. We sought to evaluate how the COVID-19 pandemic impacted typhoid epidemiology in Pakistan, from the beginning of the pandemic in 2020 ...
Carly Ching   +4 more
doaj   +1 more source

Serologic Evidence of Dengue Infection before Onset of Epidemic, Bangladesh

open access: yesEmerging Infectious Diseases, 2003
Dengue fever emerged in Bangladesh in 2000. We tested 225 serum and plasma samples from febrile patients and 184 blood donors in 1996 and 1997 for dengue antibodies; 55 (24.4%) febrile patients had dengue antibodies (65.5% with secondary infection ...
M. Anowar Hossain   +4 more
doaj   +1 more source

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