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The Lancet, 2015 Typhoid fever is a waterborne disease. There are a reported 16 million illnesses and 600,000 deaths annually (Crump, 2010). Most cases occur in developing countries; however, citizens of developed countries who visit developing ones are at risk of ...
Nicholas, Christian
core +4 more sources
Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model
Nature Medicine, 2019 Salmonella Typhi is a human host-restricted pathogen that is responsible for typhoid fever in approximately 10.9 million people annually1. The typhoid toxin is postulated to have a central role in disease pathogenesis, the establishment of chronic ...
Malick M Gibani +2 more
exaly +2 more sources
Typhoid conjugate vaccines for preventing typhoid fever (enteric fever). [PDF]
Cochrane Database Syst RevTyphoid fever is a major cause of enteric disease-related morbidity and mortality. Vaccination reduces disease burden and prevents outbreaks, but policies and programmes should be informed by the most recent evidence as newer vaccines become available.To assess the benefits and harms of typhoid conjugate vaccines (TCVs) compared to no vaccine, placebo,
Gloeck NR +6 more
europepmc +3 more sources
The burden of typhoid fever in low- and middle-income countries: A meta-regression approach
PLoS Neglected Tropical Diseases, 2017 Background Upcoming vaccination efforts against typhoid fever require an assessment of the baseline burden of disease in countries at risk. There are no typhoid incidence data from most low- and middle-income countries (LMICs), so model-based estimates ...
Marina Antillon +2 more
exaly +2 more sources
Study of Biochemical Changes and Elevated Levels of Enzymes in Salmonella typhi Infected Patients in Pakistani Population [PDF]
International Journal Bioautomation, 2012 Typhoid fever causes significant biochemical changes and hepatic complications. As many studies have indicated several biochemical parameters that are involved in developing the risk of typhoid fever. The current study was designed to evaluate these risk
Ayesha Shamim +2 more
doaj +2 more sources
The phylogeography and incidence of multi-drug resistant typhoid fever in sub-Saharan Africa
Nature Communications, 2018 There is paucity of data regarding the geographical distribution, incidence, and phylogenetics of multi-drug resistant (MDR) Salmonella Typhi in sub-Saharan Africa.
Se Eun Park, Duy Thanh Pham, Justin Im
exaly +2 more sources
The global burden of typhoid fever
Bulletin of the World Health Organization, 2004 OBJECTIVE: To use new data to make a revised estimate of the global burden of typhoid fever, an accurate understanding of which is necessary to guide public health decisions for disease control and prevention efforts.
Crump John A. +2 more
doaj +2 more sources
Preventing Foodborne Illness: Typhoid Fever—Salmonella Typhi
EDIS, 2016 Typhoid fever is a blood infection caused by the consumption of food or water contaminated with the bacterium Salmonella enterica. Typhoid fever is easily controlled and relatively uncommon in the United States, but an estimated 21.5 million people per ...
Keith R. Schneider +2 more
doaj +5 more sources