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The Lancet, 2015 Typhoid fever is a waterborne disease. There are a reported 16 million illnesses and 600,000 deaths annually (Crump, 2010). Most cases occur in developing countries; however, citizens of developed countries who visit developing ones are at risk of ...
Nicholas, Christian
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Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model
Nature Medicine, 2019 Salmonella Typhi is a human host-restricted pathogen that is responsible for typhoid fever in approximately 10.9 million people annually1. The typhoid toxin is postulated to have a central role in disease pathogenesis, the establishment of chronic ...
Malick M Gibani +2 more
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The phylogeography and incidence of multi-drug resistant typhoid fever in sub-Saharan Africa
Nature Communications, 2018 There is paucity of data regarding the geographical distribution, incidence, and phylogenetics of multi-drug resistant (MDR) Salmonella Typhi in sub-Saharan Africa.
Se Eun Park, Duy Thanh Pham, Justin Im
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The burden of typhoid fever in low- and middle-income countries: A meta-regression approach
PLoS Neglected Tropical Diseases, 2017 Background Upcoming vaccination efforts against typhoid fever require an assessment of the baseline burden of disease in countries at risk. There are no typhoid incidence data from most low- and middle-income countries (LMICs), so model-based estimates ...
Marina Antillon +2 more
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MMWR. Morbidity and mortality weekly report, 2023 Typhoid fever, an acute febrile illness caused by Salmonella enterica serovar Typhi (S. Typhi), is endemic in many low- and middle-income countries† (1).
Molly Hancuh +10 more
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Burden of typhoid and paratyphoid fever in India
New England Journal of Medicine, 2023 Background: In 2017, over half the global burden of typhoid fever was projected to have occurred in India. In the absence of contemporary population-based data, it is unclear whether declining trends of hospitalization for typhoid in India reflect ...
J. John +31 more
semanticscholar +1 more source
eLife, 2023 Background: The Global Typhoid Genomics Consortium was established to bring together the typhoid research community to aggregate and analyse Salmonella enterica serovar Typhi (Typhi) genomic data to inform public health action. This analysis, which marks
M. Carey +113 more
semanticscholar +1 more source
An integrated nationwide genomics study reveals transmission modes of typhoid fever in China
mBio, 2023 Typhoid fever, caused by Salmonella Typhi (S. Typhi), is a life-threatening disease, usually food-borne and commonly associated with international travel.
Ye Feng +15 more
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Open Forum Infectious Diseases, 2023 Typhoid fever is a serious disease that disproportionately impacts children in low-resource settings in sub-Saharan Africa, South and Southeast Asia, and the Western Pacific. The prevalence of antimicrobial-resistant strains of S.
Nginache Nampota-Nkomba +4 more
semanticscholar +1 more source