Results 11 to 20 of about 699,460 (251)

Typhoid Vaccine Acceleration Consortium Malawi: A Phase III, Randomized, Double-blind, Controlled Trial of the Clinical Efficacy of Typhoid Conjugate Vaccine Among Children in Blantyre, Malawi

Clinical Infectious Diseases, 2019
Background Typhoid fever is an acute infection characterized by prolonged fever following the ingestion and subsequent invasion of Salmonella enterica serovar Typhi (S. Typhi), a human-restricted pathogen.
James E Meiring, Matthew B Laurens, Pratiksha Patel   +2 more
exaly   +2 more sources

Efficacy of typhoid conjugate vaccine in Nepal: final results of a phase 3, randomised, controlled trial

The Lancet Global Health, 2021
Summary: Background: Typhoid fever is a major public health problem in low-resource settings. Vaccination can help curb the disease and might reduce transmission.
Mila Shakya, MPH, Merryn Voysey, DPhil, Katherine Theiss-Nyland, PhD, Rachel Colin-Jones, MA, Dikshya Pant, FCPS, Anup Adhikari, MA, Susan Tonks, BSc, Yama F Mujadidi, MSc, Peter O’Reilly, MBBCh, Olga Mazur, MSc, Sarah Kelly, MSc, Xinxue Liu, PhD, Archana Maharjan, MA, Ashata Dahal, MPH, Naheeda Haque, PharmD, Anisha Pradhan, BSc, Suchita Shrestha, MPH, Manij Joshi, BPharm, Nicola Smith, MBBCh, Jennifer Hill, PhD, Jenny Clarke, PhD, Lisa Stockdale, PhD, Elizabeth Jones, BMedSc, Timothy Lubinda, MSc, Binod Bajracharya, MD, Sabina Dongol, DPhil, Abhilasha Karkey, DPhil, Stephen Baker, ProfPhD, Gordan Dougan, ProfPhD, Virginia E Pitzer, ScD, Kathleen M Neuzil, ProfMD, Shrijana Shrestha, ProfMD, Buddha Basnyat, ProfFRCPE, Andrew J Pollard, ProfFMedSci   +33 more
doaj   +2 more sources

A forecast of typhoid conjugate vaccine introduction and demand in typhoid endemic low- and middle-income countries to support vaccine introduction policy and decisions

Human Vaccines and Immunotherapeutics, 2017
A Typhoid Conjugate Vaccine (TCV) is expected to acquire WHO prequalification soon, which will pave the way for its use in many low- and middle-income countries where typhoid fever is endemic.
Vittal Mogasale, Enusa Ramani
exaly   +2 more sources

Optimized Detoxification of a Live Attenuated Vaccine Strain (SG9R) to Improve Vaccine Strategy against Fowl Typhoid

Vaccines, 2021
The live attenuated vaccine strain, SG9R, has been used against fowl typhoid worldwide, but it can revert to the pathogenic smooth strain owing to single nucleotide changes such as nonsense mutations in the rfaJ gene.
Nam-Hyung Kim, Dae-Sung Ko, Eun-Jin Ha, Sunmin Ahn, Kang-Seuk Choi, H. Kwon   +5 more
semanticscholar   +2 more sources

Phase II multicentre double-blind randomised controlled trial of a Bivalent VaccInation against Salmonella Typhi and Paratyphi A (BiVISTA) using a controlled human infection model of paratyphoid A infection: study protocol [PDF]

BMJ Open
Introduction Enteric fever, primarily caused by Salmonella enterica Typhi and Salmonella enterica Paratyphi A (SPA), is endemic mainly in South Asia, disproportionately affecting school-age children.
Elizabeth Jones, Xinxue Liu, Andrew J Pollard, Brian Angus, Parvinder Aley, Eleanor Wilson, Hannah Robinson, Amy Flaxman, Prasad S Kulkarni, Nisha Singh, Naina McCann, Young Chan Kim, Margarete Paganotti Vicentine, Oisin Hennigan, Noshi Maria, Claudia I Juarez Molina, Stanislava Koleva, Mohammod K Islam, Nicole Day, Allison MacDonald, Mehreen Adnan, Sophie Vernon, Anirudha Vyankatesh Potey, Abhijeet Dharmadhikari, Sanket Gaidhane, Maheshi Nirmala Ramasamy   +25 more
doaj   +2 more sources

Strategies to Improve Coverage of Typhoid Conjugate Vaccine (TCV) Immunization Campaign in Karachi, Pakistan

Vaccines, 2020
The emergence and spread of extensively drug-resistant (XDR) typhoid in Karachi, Pakistan led to an outbreak response in Lyari Town, Karachi utilizing a mass immunization campaign with typhoid conjugate vaccine (TCV), Typbar TCV®.
Farah Naz Qamar, Rabab Batool, Sonia Qureshi, Miqdad Ali, Tahira Sadaf, Junaid Mehmood, Khalid Iqbal, Akram Sultan, Noah Duff, Mohammad Tahir Yousafzai   +9 more
doaj   +2 more sources

Barriers to typhoid fever vaccine access in endemic countries

Research and Reports in Tropical Medicine, 2017
M Imran Khan,1 Carlos Franco-Paredes,2,3 Sushant Sahastrabuddhe,4 R Leon Ochiai,5 Vittal Mogasale,4 Bradford D Gessner6 1Center of Excellence in Women and Child Health, The Aga Khan University, Karachi, Pakistan; 2Hospital Infantil de México ...
Khan MI, Franco-Paredes C, Sahastrabuddhe S, Ochiai RL, Mogasale V, BD Gessner   +5 more
doaj   +1 more source

Cost analysis of a nationwide typhoid conjugate vaccine campaign in Burkina Faso. [PDF]

PLoS ONE
BackgroundIn Burkina Faso, typhoid fever remains a major public health concern, particularly among children under 15. In January 2025, a nationwide campaign introduced the typhoid conjugate vaccine targeting children aged 9 months to 14 years. This study
Jean-Louis Koulidiati, Robert L Zoma, Eric I Nebié, Soumaila Yameogo, Christelle Neya Ouedraogo, Joël Arthur Kiendrébéogo, Frédéric Debellut   +6 more
doaj   +2 more sources

Impact of the COVID-19 pandemic and typhoid conjugate vaccine introduction on typhoid fever in Nepal. [PDF]

PLoS Neglected Tropical Diseases
BackgroundWhile typhoid conjugate vaccines (TCV) offer promise for reducing risk in endemic settings, their population-level impact remains unclear.
Dipesh Tamrakar, Shiva Ram Naga, Esther Jung, Basudha Shrestha, Pratibha Bista Roka, Rabin Pokharel, Sabin Bikram Shahi, Aarjya Tara Bajracharya, Surendra K Mahadup, Nishan Katuwal, Kate Doyle, Jessica C Seidman, Alice S Carter, Stephen P Luby, Isaac I Bogoch, Kristen Aiemjoy, Denise O Garrett, Rajeev Shrestha, Jason R Andrews   +18 more
doaj   +2 more sources

Live Typhoid Vaccine for IBD-Patients—Well Tolerated and with Possible Therapeutic Effect

Drug Target Insights, 2008
Background: Our incidental observation of a remarkable improvement of disease activity following vaccination against typhoid in a patient with inflammatory bowel disease (IBD) was the incentive of this pilot study.
Gunnar Nysæter, Arnold Berstad
doaj   +1 more source