Results 241 to 250 of about 1,048,377 (295)
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Current Opinion in Oncology, 1997
This review covers the literature on significant studies of small molecule inhibitors of the epidermal growth factor receptor (EGFR), platelet-derived growth factor receptor (PDGFR), fibroblast growth factor receptor (FGFR), Flk-1, and src family tyrosine kinases from 1996 through mid-1997. During this period, there has been substantial progress in the
W D, Klohs, D W, Fry, A J, Kraker
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This review covers the literature on significant studies of small molecule inhibitors of the epidermal growth factor receptor (EGFR), platelet-derived growth factor receptor (PDGFR), fibroblast growth factor receptor (FGFR), Flk-1, and src family tyrosine kinases from 1996 through mid-1997. During this period, there has been substantial progress in the
W D, Klohs, D W, Fry, A J, Kraker
openaire +2 more sources
The FASEB Journal, 1992
A major process through which environmental information is transmitted into cells is via activation of protein tyrosine kinases. Receptor tyrosine kinases contain extracellular ligand recognition, single membrane spanning, and cytoplasmic protein tyrosine kinase domains. The cytoplasmic kinase core is flanked by regulatory segments,
D L, Cadena, G N, Gill
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A major process through which environmental information is transmitted into cells is via activation of protein tyrosine kinases. Receptor tyrosine kinases contain extracellular ligand recognition, single membrane spanning, and cytoplasmic protein tyrosine kinase domains. The cytoplasmic kinase core is flanked by regulatory segments,
D L, Cadena, G N, Gill
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Tyrosine kinases in neutrophils
Current Opinion in Hematology, 1999Nonreceptor tyrosine kinases have been shown to represent essential components of several signal transduction pathways implicated in neutrophil activation. Engagement of phagocytic, cytokine, chemoattractant, and adhesion receptors transduces intracellular signals via distinct tyrosine kinases.
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Tyrosine kinases in megakaryocytopoiesis
STEM CELLS, 1995Protein-tyrosine kinases (PTKs) are of vital importance in a variety of cell functions. Recent studies have provided considerable insight into the binding of growth factors to tyrosine kinase receptors and the consequent induction of signal pathways that lead to a biologic response.
H, Avraham +5 more
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Receptor Tyrosine Kinase Signaling and Targeting in Glioblastoma Multiforme
International Journal of Molecular Sciences, 2021Jasmin Lalonde +2 more
exaly
Study of Tyrosine Kinases and Protein Tyrosine Phosphorylation
2004In recent years, our increased understanding of the complex signal transduction mechanisms that regulate cellular function has fueled huge advances in all aspects of biomedical science and cell biology. Platelet and megakaryocyte function is no exception to this. In the last 10 yr our understanding of the receptor biochemistry and the systems that they
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Tyrosine Kinase Receptors in Oncology
International Journal of Molecular Sciences, 2020Alfredo Carrato +2 more
exaly