Results 101 to 110 of about 1,520,545 (236)

In vivo precision base editing to rescue mouse models of disease

Molecular Therapy: Nucleic Acids
CRISPR base editing enables precise, irreversible base conversions without inducing double-stranded breaks (DSBs) and has gained significant attention in recent years. By converting cytosine to thymine (C→T) or adenine to guanine (A→G), base editors (BEs)
Aaron Schindeler, Julian Chu, Christal Au-Yeung, Hsien-Yin Kao, Samantha L. Ginn, Alexandra K. O’Donohue   +5 more
doaj   +1 more source

Choosing a pediatric recipient for orthotopic liver transplantation [PDF]

, 1987
Between March 3, 1981, and June 1, 1984, 216 children were evaluated for orthotopic liver transplantation. Of the 216 patients, 117 (55%) had recelved at least one liver transplant by June 1, 1985. Fifty-five (25%) died before transplantation.
Andrew H. Urbach, Atkin, Basil J. Zitelli, Borel, Byar, Byar, Byers W. Shaw, Cox, Cutler, Daniel J. Schaid, Fallon, Gartner, Gartner, Gartner, Gordon, Houssin, Howard Rockette, J. Carlton Gartner, J. Jeffrey Malatack, John Fischer, Lachin, Lee, Mantel, National Institutes of Health Consensus Development Conference statement, Perrin, Sabbeth, Shaw, Shunzaburo Iwatsuki, Starzl, Starzl, Thomas E. Starzl, Zitelli   +31 more
core   +1 more source

"A Case Report of a Female Child with Tyrosinemia Type I in Southern Philippines During the Covid-19 Pandemic"

Biomedical Journal of Scientific & Technical Research, 2023
Genelynne J Beley
semanticscholar   +1 more source

Validation of Clinical-Grade Electroporation Systems for CRISPR-Cas9-Mediated Gene Therapy in Primary Hepatocytes for the Correction of Inherited Metabolic Liver Disease

Cells
Hepatocyte transplantation (HTx) combined with ex vivo gene therapy has garnered significant interest due to its potential for treating many inherited metabolic liver diseases.
Justin Gibson, Abishek Dhungana, Menam Pokhrel, Benjamin Arthur, Pramita Suresh, Olumide Adebayo, Renee N. Cottle   +6 more
doaj   +1 more source

Hormonally and chemically defined expansion conditions for organoids of biliary tree Stem Cells

Bioactive Materials
Wholly defined ex vivo expansion conditions for biliary tree stem cell (BTSC) organoids were established, consisting of a defined proliferative medium (DPM) used in combination with soft hyaluronan hydrogels.
Wencheng Zhang, Yangyang Cui, Mengqi Lu, Mingyang Xu, Yuting Li, Haimeng Song, Yi Luo, Jinjia Song, Yong Yang, Xicheng Wang, Lijun Liao, Yunfang Wang, Lola Reid, Zhiying He   +13 more
doaj   +1 more source

Evaluation of Neonatal Screening Programs for Tyrosinemia Type 1 Worldwide

International Journal of Neonatal Screening
In The Netherlands, newborn screening (NBS) for tyrosinemia type 1 (TT1) uses dried blood spot (DBS) succinylacetone (SUAC) as a biomarker. However, high false-positive (FP) rates and a false-negative (FN) case show that the Dutch TT1 NBS protocol is ...
Allysa M. Kuypers, Marelle J. Bouva, J. Gerard Loeber, Anita Boelen, Eugenie Dekkers, Konstantinos Petritis, C. Austin Pickens, The ISNS Representatives, Francjan J. van Spronsen, M. Rebecca Heiner-Fokkema   +9 more
doaj   +1 more source

Evolution of Liver Transplantation [PDF]

, 1982
Abouna, Alper, Alper, Andres, Aune, Bechtelsheimer, Benichou, Berman, Birtch, Birtch, Borel, Borel, Brettschneider, Brölsch, Calne, Calne, Calne, Calne, Calne, Calne, Calne, Calne, Calne, Calne, Calne, Calne, Calne, Calne, Calne, Calne, Calne, Calne, Cannon, Carpenter, Corman, Craig, Daloze, Demirleau, Noureddine, Vignes, Dubois, Fennell, Fisch, Fonkalsrud, Fortner, Fortner, Franksson, Fulginiti, Gamier, Gips, Green, Groth, Groth, Groth, Herbertson, Hood, Houssin, Houssin, Hume, Hume, Hunt, Iwatsuki, Iwatsuki, Iwatsuki, Johnson, Kahan, Kashiwagi, Keown, Klintmalm, Klintmalm, Kostakis, Lampe, Lie, Limmer, Machado, Marchioro, Martineau, McDonald, Mikaeloff, Mikaeloff, Moore, Moore, Murray, Murray, Murray, Myburgh, Najarian, Neuberger, O'Donnell, Opelz, Orr, Pappas, Peacock, Penn, Picache, Pichlmayr, Porter, Portmann, Powles, Putnam, Raum, Rynasiewicz, Schroter, Schroter, Shaw, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Strober, Sweny, Terblanche, von Kaulla, Waddell, Wall, Williams, Wolff, Woodruff   +142 more
core   +1 more source

Orthotopic liver transplantation in children. Two-year experience with 47 patients [PDF]

, 1984
During a 24-month period (May 1981 to May 1983), 47 pediatric patients (ranging in age from 7 months to 18 years) underwent orthotopic liver transplantation using cyclosporine and prednisone.
Gartner, JC, Iwatsuki, S, Malatack, JJ, Shaw, BW, Starzl, TE, Zitelli, BJ   +5 more
core  

HEREDITARY TYROSINEMIA TYPE I

Journal of Pediatric Gastroenterology and Nutrition, 1991
F. J. van Spronsen, Y. Thomassen, R. Berger, G. P.A. Smit, H. S.A. Heymans   +4 more
openaire   +2 more sources

A Rapid Screening Test on Dried Blood for the Neonatal Diagnosis of Tyrosinemia Type I. [PDF]

Iran J Pediatr, 2016
Bodaghkhan F, Geramizadeh B, Rajeh AA, Haghighat M, Dehghani M, Honar N, Zahmatkeshan M, Imanieh MH.   +7 more
europepmc   +1 more source