Results 191 to 200 of about 295,660 (323)

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

TransSiamUNet based transformer-augmented Siamese-U-Net for precise change detection in satellite imagery. [PDF]

Sci Rep
Ali F, Labib SS, Mahmoud A, Fattoh IE.
europepmc   +1 more source

A Comparative Performance of U-net and Mask R-CNN for Lung Segmentation Across Public Chest X-ray Datasets

Andrew Mao
openalex   +1 more source

Automated Adolescence Scoliosis Detection Using Augmented U-Net With Non-square Kernels

, 2023
Yujie Wu, Khashayar Namdar, Chaojun Chen, Shahob Hosseinpour, Manohar Shroff, Andréa S. Doria, Farzad Khalvati   +6 more
openalex   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Filling of incomplete sinograms from sparse PET detector configurations using a residual U-Net. [PDF]

Med Phys
Leffler K, Luppino LT, Kuttner S, Söderkvist K, Axelsson J.   +4 more
europepmc   +1 more source

Enhancing U-Net segmentation performance through data augmentation and bayesian hyperparameter optimization for RSWA images

Adil Nabih, Imane Moufid, Fouad Briki, Ismail Lagrat, Oussama Bouazaoui   +4 more
openalex   +1 more source

Time-Series U-Net with Recurrence for Noise-Robust Imaging Photoplethysmography [PDF]

Vineet Shenoy, Shaoju Wu, Armand Comas, Tim K. Marks, Suhas Lohit, Hassan Mansour   +5 more
openalex   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source