Results 231 to 240 of about 44,552 (307)

Multiomics profiling and experiments in preclinical models revealed RAD51-IN-1 as a synergistic potentiator of anlotinib sensitivity. [PDF]

Sci Adv
Meng H, Chang Q, Zhang Y, Ren J, Guo H, Yu L, Qian C, Jiang Y, Zhang L, Cheng W.   +9 more
europepmc   +1 more source

Bamboo‐Like Whiskers‐Reinforced Bioceramics Accelerate Large Segmental Bone Regeneration via Dual Modulation of Type‐H Vessels and Osteoinduction

Advanced Science, EarlyView.
The graphical abstract image of bamboo‐like whisker‐reinforced Ca‐P bioceramics accelerating large segmental bone regeneration. ABSTRACT Regenerative repair of segmental bone defect remains a major clinical challenge. The conventional mental implants suffer from mechanical strength mismatch and long‐term foreign bodies presence.
Cong Feng, Haibo Teng, Chuyao Xu, Jiaze He, Keting Liu, Xueying Li, Kai Zhang, Xiangdong Zhu, Xiangfeng Li, Jianguo Xu, Xingdong Zhang   +10 more
wiley   +1 more source

Design and Implementation of a Three-Segment Tendon-Driven Continuum Robot with Variable Stiffness for Manipulation in Confined Spaces. [PDF]

Biomimetics (Basel)
Weng Z, Sha L, Chen Y, Fan B, Li L, Liu B.   +5 more
europepmc   +1 more source

Mechanically Triggered DNA Nanovehicles for Targeted Dual‐Drug Cancer Therapy

Advanced Science, EarlyView.
A mechanically triggered DNA nanovehicle is introduced that co‐releases two anticancer drugs in response to integrin‐mediated cellular forces. Cholesterol‐anchored DNA assemblies undergo force‐induced unfolding at cell–cell junctions, enabling selective, localized dual‐drug activation in cancer cells while minimizing off‐target toxicity in low‐tension ...
Murali Mohana Rao Singuru, Priyanka Bhattacharyya, Mingxu You   +2 more
wiley   +1 more source

Genetic mutations in GLP-1/Notch pathway reveal distinct mechanisms of Notch signaling in germline stem cell regulation. [PDF]

Biol Open
John NS, Urman MA, Mehmood MG, Gentile V, Lee C.   +4 more
europepmc   +1 more source

Adhesion‐Driven Removal of Microplastics From Aquatic Systems by Using Microgel Glues

Advanced Science, EarlyView.
Soft polymeric microgels function as “glues” that aggregate diverse microplastics through multivalent adhesion, promoting their interfacial deposition and co‐precipitation for efficient removal from water. Remarkably, this approach remains effective even for nanoscale plastic particles as small as 50 nm.
Jinmeng Zhang, Jie Xu, Wen Chen, Yanping Chen, Zixin Pan, Weitai Wu   +5 more
wiley   +1 more source

Characterization of di-gital, tri-gital, and tetra-gital temporal movement of systolic blood pressure on the arterial pulse waveform of rats at different vascular stiffness. [PDF]

Animal Model Exp Med
Misak A, Tomasova L, Grman M, Ondrias K.
europepmc   +1 more source

Topology‐Enriched Toughness Enhancement in Quasi‐Periodic Metastructures Featuring Tailorable Strong‐Weak Network

Advanced Science, EarlyView.
A quasi‐periodic Dart‐Kite (QDK) metastructure with a golden‐ratio‐constrained strong–weak bond network simultaneously enhances strength, toughness, and damage tolerance. Its distributed topology enables predictable, tailorable crack paths for precise fracture control and stable mechanics, demonstrating a high‐performance, controllable architecture ...
Tianyu Gao, Genda Wang, Jiabao Bai, Kai Liu   +3 more
wiley   +1 more source

Ergonomic Sponge Electrodes From Recycled PEDOT:PSS

Advanced Electronic Materials, EarlyView.
ABSTRACT Emerging technologies in human–machine interfacing increasingly aim to develop solutions that naturally conform to the body's unique characteristics. Ergonomics and electrical performance in cutaneous sensing are crucial for accurate and reliable translation of biosignals.
Matías Ceballos, Wei‐Ting Ting, Susanne Thümmler, Esma Ismailova   +3 more
wiley   +1 more source

Prediction of Fracture Loads in 3D-Printed ASA and Carbon-Fiber Reinforced ASA Notched Specimens Using the Calibrated ASED Criterion. [PDF]

Materials (Basel)
Arrieta S, Cicero S, Álvarez JA.
europepmc   +1 more source