Results 161 to 170 of about 53,720 (266)

Occurrence of and Dietary Exposure to Toxic Element Impurities in Food Additives: A Probabilistic Exposure Assessment for the Belgian Population. [PDF]

Foods
Vansnick C, Cheyns K, Montalvo D, Waegeneers N.   +3 more
europepmc   +1 more source

U-Pb ID-TIMS age of the Tiksheozero carbonatite: expression of 2.0 Ga alkaline magmatism in Karelia, Russia

Open Geosciences, 2011
Corfu Fernando, Bayanova Tamara, Shchiptsov Vladimir, Frantz Natalia   +3 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Gastric Tissue Biomonitoring Identifies Tissue-Specific Metal Profiles Associated with <i>Helicobacter pylori</i> Infection. [PDF]

Toxics
Aydin T, Turksoy VA.
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Risk factors and construction of prediction model for plastic bronchitis in children with <i>Mycoplasma pneumoniae</i> pneumonia. [PDF]

Transl Pediatr
Xin R, Yuan X, Jin J, Shu J, Ye X.
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Mineralogical and geochemical provenance reference for turquoise from the Teghout Cu-Mo deposit in Armenia. [PDF]

Sci Rep
Shirdam B, Yang M, Meliksetian K, Grigoryan E, Yang Y, Zheng Y, Wan X, Jiang Y.   +7 more
europepmc   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Peripheral and central auditory impairment linked to heavy metal exposure in Nicaraguan children from artisanal mining communities. [PDF]

J Glob Health
Kachadoorian M, Lee T, Fitzgerald J, Geffert M, Rieke C, Clavier O, Fuente A, Gui J, Zhou J, Li S, Jackson B, Karagas M, Mojica K, González-Quiroz M, Niemczak C, Buckey J, Saunders J.   +16 more
europepmc   +1 more source