Results 291 to 300 of about 668,632 (409)

Zircon U-Pb ages and Lu-Hf isotopic systematics in granites from Mt Isa Inlier − evidence of prolonged reworking of an active continental margin during the final assembly of the Nuna (Columbia) supercontinent

Sutthida Noptalung, Ioan V. Sanislav, Helen A. Cocker, Avish Kumar   +3 more
openalex   +1 more source

Post-caldera volcanism: in situ measurement of U^Pb age and oxygen isotope ratio in Pleistocene zircons from Yellowstone caldera

, 2001
I. Bindeman, J. Valley, J. Wooden, H. Persing   +3 more
semanticscholar   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Late Cenozoic river reorganization related to tectonic extrusion formed the modern drainage system in southeastern Tibet. [PDF]

Proc Natl Acad Sci U S A
Cao K, Wang G, Harrison TM, Yuan X, Leloup PH, Kusky TM, Cao L, Shen X, Cheng Y, Yao J, He X, Zhu Z, Xie S.   +12 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Dose Assessment in Mining Communities in South Africa Using Ecolego Simulation Software. [PDF]

Int J Environ Res Public Health
Dudu VP, Ilunga M, Chabalala DT, Mathuthu M.   +3 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Lights and shades of front-line treatment with covalent BTK inhibitors combined with venetoclax in patients with chronic lymphocytic leukemia. [PDF]

Oncol Rev
Visentin A, Mauro FR.
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source