The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
In situ U-Pb Dating of Calcite from the South China Antimony Metallogenic Belt. [PDF]
iScience, 2020 Luo K +6 more
europepmc +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Improvement in the Analytical Capabilities of LA-ICP-MS for High Spatial Resolution U-Pb Dating of Zircon Using Mixed-Gas Plasma. [PDF]
J Anal Methods Chem, 2020 Shenghua L +4 more
europepmc +1 more source
An archean suture zone in the Tobacco Root Mountains? (1984) Evolution of Archean Continental Crust, SW Montana (1985) [PDF]
The Lake Plateau area of the Beartooth Mountains, Montana were mapped and geochemically sampled. The allochthonous nature of the Stillwater Complex was interpreted as a Cordilleran-style continental margin.
Kain, L., Mogk, D. W.
core +1 more source
Discovery of an albite gneiss from the Ile de Groix (Armorican Massif, France): geochemistry and LA-ICP-MS U-Pb geochronology of its Ordovician protolith [PDF]
, 2018 For the first time, an albite orthogneiss has been recognised and dated within the HP-LT blueschist facies metabasites and metapelites of the Ile de Groix.
Ballèvre, Michel +4 more
core
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Luminescence dating of ditch fills from the Headland Archaeology Ltd. excavation of Newry Ring Fort, Northern Ireland [PDF]
, 2008 This study supports a new investigation into the construction, occupation and utilisation history of a Mediaeval ring fort near Newry, southwest Northern Ireland (section 2).
Burbidge, C.I. +2 more
core
Aging and Cancer, EarlyView.This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source