Results 41 to 50 of about 3,361 (218)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

High Spatial Resolution U-Pb Dating of Low-Uranium Calcite Using LA-MC-ICP-MS

Yankuang ceshi
The combination of carbonate minerals with the U-Pb isotope dating system provides direct temporal constraints for geoscientific applications. LA-MC-ICP-MS with its high sensitivity and accuracy, has been successfully applied to the high spatial ...
Chenxi ZHANG, Yuxin XIONG, Jiali FU, Wei ZHAO, Lei SHU, Zengsheng LI, Jun XU, Changxiang ZHOU, Fei HONG   +8 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

U‐Pb Geochronology of Paleosol Carbonate Cements by LA‐ICP‐MS: A Proof of Concept and Strategy for Dating the Terrestrial Record

Geochemistry, Geophysics, Geosystems
This study investigates the potential of laser ablation inductively coupled plasma mass spectrometry (LA‐ICP‐MS) U‐Pb dating for carbonate nodules in the Late Triassic Ischigualasto Formation of northwestern Argentina.
L. E. Aguirre Palafox, A. Möller, N. M. McLean, G. A. Ludvigson, C. E. Colombi, I. P. Montañez   +5 more
doaj   +1 more source

U-Pb LA-ICP-MS DATING OF DETRITAL ZIRCON FROM UPPER PERMIAN SANDSTONE OF THE BOYEVAYA GORA SECTION (ORENBURG REGION, SOUTHERN CIS-URALS)

Геодинамика и тектонофизика, 2022
The first results of U-Pb LA-ICP-MS dating of 150 detrital zircon grains from the Upper Permian sandstone of the Boyevaya Gora section (Orenburg region, the Southern Cis-Urals) are presented. 95 conditional zircon U-Pb isotopic dates form two age peaks –
A. V. Chistyakova, A. V. Ivanov, N. V. Bryanskiy, R. V. Veselovskiy, T. I. Golovanova, V. K. Golubev   +5 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Age Determination of Gem-Quality Green Vanadium Grossular (Var. Tsavorite) from the Neoproterozoic Metamorphic Mozambique Belt, Kenya and Tanzania

Crystals
Gem-quality garnets, with their high closure temperature (750–800 °C), high transparency, uniform composition, and purity, offer promising prospects for U-Pb dating.
Siyi Zhao, Bo Xu, Yi Zhao
doaj   +1 more source

Laser ablation in situ U-Pb dating and its application to diagenesis-porosity evolution of carbonate reservoirs

Petroleum Exploration and Development, 2019
Through the development and calibration of a reference material which is 209.8 Ma old using a newly-developed Laser Ablation (LA) Multi-Collector Inductively Coupled Plasma Mass Spectrometry (MC-ICP-MS) technique, we successfully overcome the difficulty ...
Anjiang SHEN, Anping HU, Ting CHENG, Feng LIANG, Wenqing PAN, Yuexing FENG, Jianxin ZHAO   +6 more
doaj   +1 more source

U–Th whole rock data and high spatial resolution U–Th disequilibrium and U–Pb zircon ages of Mt. Erciyes and Mt. Hasan Quaternary stratovolcanic complexes (Central Anatolia)

Data in Brief, 2020
Thirty-eight lava and pyroclastic samples were collected from Mt. Erciyes and Mt. Hasan, the two largest stratovolcanic complexes of the Central Anatolian Volcanic Province in Turkey.
Bjarne Friedrichs, Axel K. Schmitt, Lucy McGee, Simon Turner   +3 more
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source