Results 61 to 70 of about 381 (215)

AARS1‐Mediated RUNX3 K193 Lactylation Enhances the Activation and Cytotoxicity of CD8+T Cells in Smoking‐Related Emphysema

Advanced Science, EarlyView.
Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu, Jiaheng Lin, Yifan Li, Qiaoqiao Zhou, Min Yu, Cheng Cheng, Kang Chang, Dang Lin, Tao Bian, Yan Wu, Lu Lu, Haibo Xia, Qizhan Liu   +12 more
wiley   +1 more source

Shrimp U-Pb age and Sr-Nd isotopes of the Morro do Baú mafic intrusion: implications for the evolution of the Arenópolis volcano-sedimentary sequence, Goiás Magmatic Arc

Anais da Academia Brasileira de Ciências, 2003
The Arenópolis volcano-sedimentary sequence is located in the southern part of the Goiás Magmatic Arc and includes a ca. 900 Ma calc-alkaline arc sequence made of volcanic rocks ranging in composition from basalts to rhyolites, metamorphosed under ...
Márcio M. Pimentel, Maria Helena B. M. Hollanda, Richard Armstrong   +2 more
doaj   +1 more source

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

Advanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv, Lei Zhang, Fei Fei, Zhibin Wu, Xiuquan Wu, Ya‐nan Dou, Yihao Fu, Hao Chang, Yujie Qiang, Huaxia Xie, Ni An, Leiying Chen, Hongchen Zhang, Min‐Wen Zheng, Hongqing Chen, Xia Li, Zhou Fei   +16 more
wiley   +1 more source

U-Pb dating of niobium minerals from the pyrochlore group (Ilmeny-Vishnevogorsky carbonatite-miaskite complex, South Urals)

Литосфера, 2020
The article covers the U-Pb dating of minerals belonging to the pyrochlore group from the rare-metal ore deposits of Ilmeny-Vishnevogorsky carbonatite-miaskite complex (South Urals). Individual pyrochlore crystals were dated through a new technique of in-
I. L. Nedosekova, V. A. Koroteev, B. V. Belyatsky, V. V. Sharygin, Е. N. Lepechinа, S. V. Pribavkin   +5 more
doaj  

Optimization of Analytical Conditions for LA-ICP-MS and Its Application to Zircon U-Pb Dating

Yankuang ceshi, 2016
During LA-ICP-MS analysis, the key factor influencing data accuracy of sample analysis is whether the sample can be uniformly delivered from the laser sample chamber to the torch of the ICP-MS.An external container between LA and ICP-MS and a multi ...
LI Feng-chun, HOU Ming-lan, LUAN Ri-jian, LIN Pei-jun, LI Zeng-sheng, ZHAO Long, WANG Ji-lin, XU Shuang   +7 more
doaj   +1 more source

Single‐Cell Transcriptomics and Metabolomics Reveal Glutamate Dehydrogenase as a Central Regulator of Nitrogen Metabolic Remodeling During Alkalinity Adaptation in Crustaceans

Advanced Science, EarlyView.
Single‐cell transcriptomics reveals the cellular response of Macrobrachium hainanense to carbonate alkalinity stress. Alkalinity stress impairs branchial ammonia excretion, induces mitochondrial dysfunction, and drives cell‐type‐specific changes in gills and hemocytes.
Yiting Jin, Zhimin Lv, Chao Bian, Qibin Yang, Na Zhou, Jianguang Qin, Shengming Sun   +6 more
wiley   +1 more source

Maternal Exercise Rescues Embryonic Osteogenesis Impaired due to POLG Mutation Through a Potential Apelin‐ATF4 Axis

Advanced Science, EarlyView.
Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae, Ryan C. Riddle, Zhihua Jiang, Chaeyoung Shin, Min Du, Jun Seok Son   +5 more
wiley   +1 more source

Assessing the Impact of Promotions on Consumer Purchasing Behavior During Crises

Agribusiness, EarlyView.
ABSTRACT Understanding how households modify their food expenditure decisions during times of crisis is essential because consumer purchasing behavior frequently changes during these times. This study looks at these behavioral shifts during the COVID‐19 pandemic, concentrating on how price sensitivity and response to sales promotions changed over the ...
Wafa Mehaba, José María Gil
wiley   +1 more source

U-Pb zircon in situ dating with LA-MC-ICP-MS using a mixed detector configuration

Anais da Academia Brasileira de Ciências, 2012
The LA-MC-ICP-MS method applied to U-Pb in situ dating is still rapidly evolving due to improvements in both lasers and ICP-MS. To test the validity and reproducibility of the method, 5 different zircon samples, including the standard Temora-2, ranging ...
Farid Chemale Jr, Koji Kawashita, Ivo A. Dussin, Janaína N. Ávila, Dayvisson Justino, Anelise Bertotti   +5 more
doaj  

Characterization and Selection of Contractile Actuators for Soft Robotics Operating in the Quasistatic Regime

Advanced Intelligent Systems, EarlyView.
We developed methods to characterize soft contractile actuators using force–displacement measurements in the passive state and the total force in the active state and define the operational range of thermal, electrothermal, and pneumatic muscles. A graphical method enables the selection of an actuator based on the required mechanical force–displacement
Qiong Wang, Liuyang Cheng, Jeongmin Kim, Samuel Tsai, Devin Roach, Sameh Tawfick   +5 more
wiley   +1 more source