Results 201 to 210 of about 1,169,342 (222)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Coexisting autoimmune pancreatitis and pancreatic adenocarcinoma: Diagnostic challenges and case insights. [PDF]

open access: yesRadiol Case Rep
Qajia H   +6 more
europepmc   +1 more source

Syphilis Infection Triggering Autoimmune Hepatitis. [PDF]

open access: yesACG Case Rep J
Namazian S   +4 more
europepmc   +1 more source

Microscopic Polyangiitis After Pulmonary Nontuberculous Mycobacterial Disease: A Case Report and Literature Review. [PDF]

open access: yesRespirol Case Rep
Takahashi H   +11 more
europepmc   +1 more source

Severe Acute Liver Injury Following Repeated Supratherapeutic Paracetamol Ingestion in a Child: A Case Report from a Resource-Limited Setting. [PDF]

open access: yesInt Med Case Rep J
Hassan RA   +7 more
europepmc   +1 more source

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