On the Edgeworth Expansion and the Bootstrap Approximation for a Studentized $U$-Statistic [PDF]
, 1991 Roelof Helmers
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Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
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Testing for stochastic monotonicity [PDF]
We propose a test of the hypothesis of stochastic monotonicity. This hypothesis is of interest in many applications in economics. Our test is based on the supremum of a rescaled U-statistic. We show that its asymptotic distribution is Gumbel.
Oliver Linton +2 more
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U-Statistics for Change under Alternatives
Journal of Multivariate Analysis, 2001 AbstractAsymptotic distributions of U-statistics to test for possible changes in the distribution will be derived when the change occurred. We will show that for all possible types of kernels, symmetric, antisymmetric, degenerate, non-degenerate, the test statistics are asymptotically normally distributed.
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Molecular Oncology, EarlyView.Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu +11 more
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A Consistent Nonparametric Test for Causality in Quantile [PDF]
This paper proposes a nonparametric test of causality in quantile. Zheng (1998) has proposed an idea to reduce the problem of testing a quantile restriction to a problem of testing a particular type of mean restriction in independent data.
Kiho Jeong, Wolfgang Härdle
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Data filtering in statistical studies of flares recorded in sky fields of stellar aggregates - demonstrated with the example of the Pleiades [PDF]
, 1990 G. Szécsényi-Nagy
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Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
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Binney/Dowrick: The Theory of Critical Phenomena/Brown: Quantum Field Theory/Lifshin: Materials Science and Technology: Vol. 2A, Characterization of Materials, Part I/Cowley: Electron Diffraction Techniques, Volume 1/Bellac: Quantum and Statistical Field Theory/Hehl, Winkelmann u Meyer: Computer‐Algebra/Enderlein u Schenk: Grundlagen der Halbleiter‐physik/Lossau: Wenn Computer denken lernen: Neuronale Netzwerke/Galison u Hevley: Big Science: The Growth of Large‐Scale Research [PDF]
, 1993 Reimer Kühn +9 more
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Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
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