Results 171 to 180 of about 99,558 (321)
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
Semina: Ciências Sociais e Humanas, 1980 O objetivo deste estudo foi verificar as possíveis relações entre três variáveis-critério de realização em leitura: Inventário de Capacidades Primárias de Valett, atribuição de notas pelos professores e desempenho dos sujeitos numa tarefa de ditado de ...
Maria Aparecida Trevisan Zamberlan +1 more
doaj
Confidence in U. S. Federal Statistical Agencies [PDF]
, 2015 Jennifer Hunter Childs +2 more
openalex +1 more source
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Semi-supervised datasets are ubiquitous across diverse domains where obtaining fully labeled data is costly or time-consuming. The prevalence of such datasets has consistently driven the demand for new tools and methods that exploit the potential of unlabeled data.
Kim, Ilmun +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Revista Brasileira de Cineantropometria e Desempenho Humano, 2013 In long distance swimming competitions, the optimal pacing strategy is not well established. The objective of this study was to characterize the pacing strategy adopted by international level athletes in 800-m (female) and 1500-m (male) crawl swimming ...
Mayara Vieira Damasceno +6 more
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