Results 181 to 190 of about 100,609 (297)

Statistical study of the prompt-fission γ-ray spectrum for U238(n, f) in the fast-neutron region [PDF]

, 2018
Liqiang Qi, M. Lebois, J. N. Wilson, A. Chatillon, S. Courtin, G. Fruet, G. Georgiev, D. G. Jenkins, B. Laurent, L. Le Meur, A. Maj, P. Marini, I. Matéa, L. Morris, V. Nanal, P. Napiorkowski, A. Oberstedt, S. Oberstedt, C. Schmitt, O. Sérot, M. Stănoiu, B. Wasilewska   +21 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Shaping Somalia's environmental sustainability: the role of institutional quality, renewable energy, economic growth, and financial globalization on load capacity factor. [PDF]

Sci Rep
Daror HO, Warsame AA, Ahmed Z.
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

SAI: A Python Package for Statistics for Adaptive Introgression. [PDF]

Mol Biol Evol
Huang X, Chen S, Hackl J, Kuhlwilm M.
europepmc   +1 more source

MSU-Net: Multiscale Statistical U-Net for Real-time 3D Cardiac MRI Video Segmentation [PDF]

, 2019
Tianchen Wang, Jinjun Xiong, Xiaowei Xu, Meng Jiang, Yiyu Shi, Haiyun Yuan, Meiping Huang, Jian Zhuang   +7 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Clinical Outcomes and Perioperative Morbidity in Obstructive Versus Elective Colorectal Cancer: A 10-Year Retrospective Analysis. [PDF]

Cureus
Kannummal Veetil S, Jain D, David Haque P, Khurana S.   +3 more
europepmc   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Implementation of a Hot Gallbladder Service at a District General Hospital: A 15-Month Review. [PDF]

Cureus
Cui XC, Zaman O, Naqvi M.
europepmc   +1 more source