Results 61 to 70 of about 99,558 (321)

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Testing for Changes in Kendall's Tau [PDF]

open access: yes, 2016
For a bivariate time series $((X_i,Y_i))_{i=1,...,n}$ we want to detect whether the correlation between $X_i$ and $Y_i$ stays constant for all $i = 1,...,n$.
Aue   +38 more
core   +2 more sources

Prognostic impact of alkaline phosphatase for in-hospital mortality in patients with acute coronary syndrome: a prospective cohort study in China

open access: yesBMJ Open, 2019
ObjectivesAlkaline phosphatase (ALP) can promote vascular calcification, but the association between ALP and in-hospital mortality in patients with acute coronary syndrome (ACS) is not well defined.DesignA prospective cohort study.Setting and ...
Tongtong Yu   +8 more
doaj   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Moments and central limit theorems for some multivariate Poisson functionals

open access: yes, 2014
This paper deals with Poisson processes on an arbitrary measurable space. Using a direct approach, we derive formulae for moments and cumulants of a vector of multiple Wiener-It\^o integrals with respect to the compensated Poisson process.
Billingsley   +7 more
core   +1 more source

PENGARUH TEKNIK RELAKSASI TERHADAP PERUBAHAN STATUS MENTAL KLIEN SKIZOFRENIA DI RUMAH SAKIT JIWA DAERAH SURAKARTA

open access: yesJurnal Berita Ilmu Keperawatan, 2008
Background: The complexity and hardly living and the increasing of psychosocial stress maker cause human disable to prevent the pressure of live. Critical condition brings the effect to the increasing of mental emotional disease, and one of them of the
Erviana Kustanti, Arif Widodo
doaj   +1 more source

A Consistent Nonparametric Test for Granger Non-Causality Based on the Transfer Entropy

open access: yesEntropy, 2020
To date, testing for Granger non-causality using kernel density-based nonparametric estimates of the transfer entropy has been hindered by the intractability of the asymptotic distribution of the estimators. We overcome this by shifting from the transfer
Cees Diks, Hao Fang
doaj   +1 more source

A Bivariate Extension of the $U$ Statistic [PDF]

open access: yesThe Annals of Mathematical Statistics, 1951
Let $x, y$, and $z$ be three random variables with continuous cumulative distribution functions $f, g$, and $h$. In order to test the hypothesis $f = g = h$ under certain alternatives two statistics $U, V$ based on ranks are proposed. Recurrence relations are given for determining the probability of a given $(U, V)$ in a sample of $l x$'s, $m y$'s, $n ...
openaire   +2 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

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