Results 81 to 90 of about 99,558 (321)
LDP for inhomogeneous U-statistics
The Annals of Applied Probability41 ...
Bhattacharya, Sohom +2 more
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FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source
A U-Statistic for Testing the Lack of Dependence in Functional Partially Linear Regression Model
MathematicsThe functional partially linear regression model comprises a functional linear part and a non-parametric part. Testing the linear relationship between the response and the functional predictor is of fundamental importance.
Fanrong Zhao, Baoxue Zhang
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A renewal approach to Markovian U-statistics [PDF]
Mathematical Methods of Statistics, 2011 In this paper we describe a novel approach to the study of U-statistics in the Markovian setup based on the (pseudo-) regenerative properties of Harris Markov chains. Exploiting the fact that any sample path X1, ..., Xn of a general Harris chain X may be divided into asymptotically i.i.d.
Bertail, Patrice, Clémençon, Stéphan
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Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Apstract: Applied Studies in Agribusiness and Commerce, 2015 Agricultural produce certification is synonymous to farm assurance of which cocoa certification is an example; dealing with issues of Good Agricultural, Environmental and Social Practices (GAP, GEP and GSP) in cocoa production.
A. B. Oreyemi +4 more
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On the invariance principle for U-statistics
Stochastic Processes and their Applications, 1979 AbstractLet Tn be a U-statistic and Sn its projection (in the sense of Hájek). Limit theory for U-statistics is usually considered in two disjoint cases, termed degenerate and nondegenerate. The traditional method is to treat the cases separately, using different techniques in each to obtain a solution.
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Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
Interpreting Kendall’s Tau and Tau-U for single-case experimental designs
Cogent Psychology, 2018 Tau (τ), a nonparametric rank order correlation statistic, has been applied to single-case experimental designs with promising results. Tau-U, a family of related coefficients, partitions variance associated with changes in trend and level.
Daniel F. Brossart +2 more
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Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source