Results 101 to 110 of about 563,530 (312)

Change point detection in high dimensional data with U-statistics [PDF]

, 2022
B. Cooper Boniece, Lajos Horváth, Peter Martin Jacobs   +2 more
openalex   +1 more source

A Location Estimator Based on a $U$-Statistic

The Annals of Statistics, 1977
Let $X_1, \cdots, X_n$ be i.i.d. $F$, and estimate the median of $F$ by the median $T_\beta$ of $\beta X_i + (1 - \beta)X_j, i \neq j$, where $\beta$ is a fixed positive constant. Then $T_\beta$ is the solution of a $U$-statistic equation from which its asymptotic normality is readily derived. The asymptotic relative efficiency of $T_\beta$ is computed
Maritz, J. S., Wu, Margaret, Stuadte, R. G.   +2 more
openaire   +3 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Characterization of Exponential Distribution Through Normalized Spacing of Generalized Order Statistics

Journal of Statistical Theory and Applications (JSTA), 2019
In this paper, exponential distribution is characterized by normalized spacing of generalized order statistics (gos) using Meijer's G-function. While the necessary part of the theorem was given by U. Kamps, E. Cramer, Statistics.
M. J. S. Khan, S. Iqrar, M. Faizan
doaj   +1 more source

Private Protocols for U-Statistics in the Local Model and Beyond [PDF]

, 2019
James Bell, Aurélien Bellet, Adrià Gascón, Tejas Kulkarni   +3 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Re‐evaluating fetal scalp pH thresholds: An examination of fetal pH variations during labor

Acta Obstetricia et Gynecologica Scandinavica
Introduction Since the 1970s, fetal scalp blood sampling (FSBS) has been used as a second‐line test of the acid–base status of the fetus to evaluate fetal well‐being during labor.
Aude Girault, Camille Le Ray, Charles Garabedian, François Goffinet, Xavier Tannier   +4 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Limit Theorems in the Nonparametric Conditional Single-Index U-Processes for Locally Stationary Functional Random Fields under Stochastic Sampling Design

Mathematics
In his work published in (Ann. Probab. 19, No. 2 (1991), 812–825), W. Stute introduced the notion of conditional U-statistics, expanding upon the Nadaraya–Watson estimates used for regression functions.
Salim Bouzebda
doaj   +1 more source