Results 131 to 140 of about 569,923 (314)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

On the Berry-Esseen Theorem for $U$-Statistics [PDF]

, 1977
Yin Chan, John C. Wierman
openalex   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Assessment of U = U knowledge and influencing factors among the population in Henan Province China based on an internet-based survey

Scientific Reports
This study evaluates the level of knowledge and the influencing factors related to the U = U (undetectable = untransmittable) concept among residents of Henan Province, China, using an online questionnaire.
Bowen Zhao, Yuan Hu, Qiongqiong Huang, Jialing Peng, Ruiling Li   +4 more
doaj   +1 more source

Private Protocols for U-Statistics in the Local Model and Beyond [PDF]

, 2019
James Bell, Aurélien Bellet, Adrià Gascón, Tejas Kulkarni   +3 more
openalex   +1 more source

Inference on Income Inequality and Tax Progressivity Indices: U-Statistics and Bootstrap Methods [PDF]

This paper discusses asymptotic and bootstrap inference methods for a set of inequality and progressivity indices. The application of non-degenerate U-statistics theory is described, particularly through the derivation of the Suits-progressivity index ...
Raquel Andres, Samuel Calonge
core  

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Management and outcomes of women with placenta accreta spectrum grade 3: an INOSS multicountry multiperiod population-based study

BMC Pregnancy and Childbirth
Background Management and outcomes in women with placenta accreta spectrum grade 3 are rarely reported from population-based studies. The objective of this study is to describe profiles, management, and outcomes, of women with placenta accreta spectrum ...
Anne Pinton, Sara Ornaghi, Marian Knight, Loïc Sentilhes, Serena Donati, Gilles Kayem, Catherine Deneux-Tharaux   +6 more
doaj   +1 more source

Guided Decision Tree: A Tool to Interactively Create Decision Trees Through Visualization of Subsequent LDA Diagrams

Applied Sciences
Decision trees are a widely used machine learning technique due to their ease of interpretation and construction. This method allows domain experts to learn from raw data, but they cannot include their prior knowledge in the analysis due to its automatic
Miguel A. Mohedano-Munoz, Laura Raya, Alberto Sanchez   +2 more
doaj   +1 more source

Approximating Symmetrized Estimators of Scatter via Balanced Incomplete U-Statistics [PDF]

, 2022
Lutz Duembgen, Klaus Nordhausen
openalex   +1 more source