Results 131 to 140 of about 4,122,773 (336)

Re‐evaluating fetal scalp pH thresholds: An examination of fetal pH variations during labor

Acta Obstetricia et Gynecologica Scandinavica
Introduction Since the 1970s, fetal scalp blood sampling (FSBS) has been used as a second‐line test of the acid–base status of the fetus to evaluate fetal well‐being during labor.
Aude Girault, Camille Le Ray, Charles Garabedian, François Goffinet, Xavier Tannier   +4 more
doaj   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Book Reviews

Austrian Journal of Statistics, 2016
Empirische Forschungsmethoden. (W. Stier) Mathematical Statistics. A Unified Introduction. (G.R. Terrell) Multivariate statistische Methoden und ihre Anwendungen in den Wirtschafts- und Sozialwissenschaften. (H.P. Litz) Local Regression and Likelihood.
Ulrike Leopold-Wildburger, Jürgen Pilz, Peter Filzmoser, Herwig Friedl, Walter Böhm, Reinhard Viertl, Aurel Schubert, Josef Richter   +7 more
doaj   +1 more source

Statistics (U) [PDF]

, 1966
M. Ullman
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

FDE-Testset: Comparing Matlab© Codes for Solving Fractional Differential Equations of Caputo Type

Fractal and Fractional
Fractional differential equations (FDEs) have attracted more and more attention in the last years; among them, equations of Caputo type allow for “more natural” initial conditions when the order is greater than one.
Luigi Brugnano, Gianmarco Gurioli, Felice Iavernaro, Mikk Vikerpuur   +3 more
doaj   +1 more source

The Edgeworth Expansion for $U$-Statistics of Degree Two [PDF]

, 1986
P. J. Bickel, Friedrich Götze, W. R. van Zwet   +2 more
openalex   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

High-Dimensional U-Statistics Type Hypothesis Testing via Jackknife Pseudo-Values with Multiplier Bootstrap

Mathematics
High-dimensional parameter testing is commonly used in bioinformatics to analyze complex relationships in gene expression and brain connectivity studies, involving parameters like means, covariances, and correlations.
Mingjuan Zhang, Libin Jin
doaj   +1 more source