Prikaz knjige “Financial Econometrics, Mathematics and Statistics: Theory, Method and Application”
Ekonomski Vjesnik, 2020 Kvantitativne financije danas predstavljaju neizostavan dio cjelokupnoga menadžmenta portfelja. Pritom je potrebno imati znanja iz područja financija, matematike, ekonometrije i statistike.
Tihana Škrinjarić
doaj
On Differentially Private U Statistics
We consider the problem of privately estimating a parameter $\mathbb{E}[h(X_1,\dots,X_k)]$, where $X_1$, $X_2$, $\dots$, $X_k$ are i.i.d. data from some distribution and $h$ is a permutation-invariant function. Without privacy constraints, standard estimators are U-statistics, which commonly arise in a wide range of problems, including nonparametric ...
Chaudhuri, Kamalika +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Empirical Bernstein Inequalities for U-Statistics
, 2010 International audienceWe present original empirical Bernstein inequalities for U-statistics with bounded symmetric kernels q. They are expressed with respect to empirical estimates of either the variance of q or the conditional variance that appears in ...
Anthoine, Sandrine +2 more
core +1 more source
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
Geographical Notices. No. XV, Arctic Explorations- The Hayes Expedition, Hall's Search for the Relics of Franklin's Expedition, Capt. Parker Snow's Proposal to Search for the Franklin Relics, Heuglin's Search for Dr. Vogel in Central Africa, Medical Statistics of the U. S. Army: Squiers's Collection of Original Documents concerning the discovery of America [PDF]
D. C. Gilman
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Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
RATES OF CONVERGENCE IN DISTRIBUTION OF A LINEAR COMBINATION OF U-STATISTICS FOR NON-DEGENERATE KERNEL [PDF]
, 2002 Koichiro Toda, Hajime Yamato
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Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source