Results 191 to 200 of about 4,122,773 (336)
Long‐term statistics of tropospheric attenuation from the Ka/U band ITALSAT satellite experiment in the United Kingdom [PDF]
S. Ventouras+2 more
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Semi-supervised datasets are ubiquitous across diverse domains where obtaining fully labeled data is costly or time-consuming. The prevalence of such datasets has consistently driven the demand for new tools and methods that exploit the potential of unlabeled data.
Kim, Ilmun+3 more
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Statistics of
Florian Gmeiner, Maren Stein
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C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Studentized Processes of U-statistics
A uniform in probability approximation is established for Studentized processes of non degenerate U-statistics of order m greater or equal to 2 in terms of a standard Wiener process. The classical condition that the second moment of kernel of the underlying U-statistic exists is relaxed to having 5/3 moments. Furthermore, the conditional expectation of
openaire +2 more sources
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach+8 more
wiley +1 more source
ASYMPTOTIC COMPARISONS OF U-STATISTICS, V-STATISTICS AND LIMITS OF BAYES ESTIMATES BY DEFICIENCIES
Toshifumi Nomachi, Hajime Yamato
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