Results 271 to 280 of about 569,923 (314)

Effect of Spatial Orientation of Fibers on Fracture Resistance of Large Mesio-Occluso-Distal Cavities in Maxillary Premolars: An In Vitro Study. [PDF]

Cureus
Vatsa G, Wang CK, Pal S, Singh AK, Kumar A.   +4 more
europepmc   +1 more source

Multiple change-points detection based on U-Statistics under weak dependence [PDF]

Ngatchou-Wandji, Joseph, Elharfaoui, Echarif, Harel, Michel   +2 more
openalex  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Correction for Dong et al., Hybridoma-inspired strategy crafts tailored multifunctional exosomes for precision therapy. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Group-Sequential Designs With an Externally-Driven Change of Primary Endpoint. [PDF]

Stat Med
Yarahmadi A, Dodd LE, Horby P, Jaki T, Stallard N.   +4 more
europepmc   +1 more source

Extending Gossip Algorithms to Distributed Estimation of U-Statistics

, 2016
Igor Colin, Joseph Salmon
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Multiple modes of AFM reveal distinct mechanical properties for dystrophin and utrophin not manifest by small fragments. [PDF]

Proc Natl Acad Sci U S A
Hua C, Vavra J, Powers J, Muretta JM, Ervasti JM, Salapaka MV.   +5 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Securing IoT Vision Systems: An Unsupervised Framework for Adversarial Example Detection Integrating Spatial Prototypes and Multidimensional Statistics. [PDF]

Sensors (Basel)
Wang N, Li J, Zhang C, Zhang D.
europepmc   +1 more source