Results 71 to 80 of about 563,530 (312)
Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1
FEBS Letters, EarlyView.Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji +5 more
wiley +1 more source
Large deviations for U-statistics
Journal of Multivariate Analysis, 1992 A large deviation principle (LDP) is proved for a large class of \(U\)- statistics. The proof is mainly based on the spectral decomposition of the kernel together with a corresponding application of the Donsker- Varadhan LDP in \(l_ 2\).
openaire +1 more source
Extending Gossip Algorithms to Distributed Estimation of U-Statistics [PDF]
, 2015 Efficient and robust algorithms for decentralized estimation in networks are essential to many distributed systems. Whereas distributed estimation of sample mean statistics has been the subject of a good deal of attention, computation of $U$-statistics ...
Bellet, Aurélien +3 more
core +2 more sources
Cram\'{e}r-type moderate deviations for Studentized two-sample $U$-statistics with applications
, 2016 Two-sample $U$-statistics are widely used in a broad range of applications, including those in the fields of biostatistics and econometrics. In this paper, we establish sharp Cram\'{e}r-type moderate deviation theorems for Studentized two-sample $U ...
Chang, Jinyuan +2 more
core +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Scaling-up Empirical Risk Minimization: Optimization of Incomplete U-statistics [PDF]
, 2016 In a wide range of statistical learning problems such as ranking, clustering or metric learning among others, the risk is accurately estimated by $U$-statistics of degree $d\geq 1$, i.e.
Bellet, Aurélien +2 more
core +2 more sources
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Topological terms of (2+1)d flag-manifold sigma models
Journal of High Energy Physics, 2021 We examine topological terms of (2 + 1)d sigma models and their consequences in the light of classifications of invertible quantum field theories utilizing bordism groups.
Ryohei Kobayashi +3 more
doaj +1 more source
A Bivariate Extension of the $U$ Statistic
The Annals of Mathematical Statistics, 1951 Let $x, y$, and $z$ be three random variables with continuous cumulative distribution functions $f, g$, and $h$. In order to test the hypothesis $f = g = h$ under certain alternatives two statistics $U, V$ based on ranks are proposed. Recurrence relations are given for determining the probability of a given $(U, V)$ in a sample of $l x$'s, $m y$'s, $n ...
openaire +2 more sources
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source