Results 221 to 230 of about 16,532,252 (340)

Pulmonary Embolism as a Rare Complication of Anaplasmosis: A Case Report. [PDF]

Cureus
Varwani N, Ahmed A, Khan SJ, Adeoshun L.
europepmc   +1 more source

Predicting Macrophage Spatial Localization from Single‐Cell Transcriptomes to Uncover Disease Mechanisms

Advanced Science, EarlyView.
This study presents a machine‐learning framework entitled MERLIN that infers the microanatomical localization of macrophages from single‐cell transcriptomic data in structured organs such as the kidney and brain. Applying this method to existing datasets from models of acute kidney injury and diabetic nephropathy uncovered spatially resolved insights ...
Junping Yin, Qi Mei, Hans‐Joachim Paust, Ning Song, Yu Zhao, Daniela Klaus, Melanie Eichler, Yijun Hua, Jie Qin, Weiting Cheng, Christina K. Weisheit, Veronika Lukacs‐Kornek, Isis Ludwig‐Portugall, Sibylle von Vietinghoff, Christian F. Krebs, Johanna Klughammer, Ulf Panzer, Christian Kurts, Jian Li   +18 more
wiley   +1 more source

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

Advanced Science, EarlyView.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon, Kyungchul Noh, Minkyu Hwang, Yoon‐Jung Kim, Unjin Lee, Yeon Joo Ryu, Je‐Kyung Ryu, Sang Beom Jun, Se‐Young Choi, Woo‐Hyun Cho, Sung Joong Lee   +10 more
wiley   +1 more source

Erratum: Goga A, Ramraj T, Cloete J, Mawela D, Waggie Z, Archary M, Chinniah K, Jeena P, Tabane NE, Van Zyl R, Reubenson G, Strehlau R, Feucht U, Reddy T, Mchunu N, Cawood S, Zühlke L, Webb K, Zar HJ, Donald KA, Scott C, Morrow BM, Aldersley T, du Plessis NM, Chetty T, Velaphi S, Dangor Z, Moore DP. Severe, primary, and incidental COVID-19 in hospitalised children, South Africa: 2020-2023. J Glob Health. 2026;16:04009. [PDF]

J Glob Health
Journal of Global Health Editorial Team.
europepmc   +1 more source

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

Advanced Science, EarlyView.
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel, Anna Meurer, Badeel Kh. Q. Zaghla, Bilge Atay, Daniel Steiert, Luca V. Hummel, Konstandina Isaakidis, Chuanbing Zang, Michael Korenkov, Marlon Schielin, Schayan Yousefian, Shima Mecklenbräuker, Marieluise Kirchner, Simon Haas, Antonia Busse, Philipp Mertins, Stefan Müller, Matthias Wirth, Martin G. Klatt, Ulrich Keller   +19 more
wiley   +1 more source

Risk prediction models for detecting a new diagnosis of heart failure within 5 years in the community: a systematic review. [PDF]

BMJ Open
Thaitirarot C, Sze S, Jones N, Barker J, Chan A, Hobbs FDR, Taylor KS, Taylor CJ.   +7 more
europepmc   +1 more source

ANOMALIAS AEROGAMAESPECTROMÉTRICAS (K, U E TH) DA QUADRÍCULA DE ARARAS-SP E SUAS RELAÇÕES COM PROCESSOS PEDOGENÉTICOS E FERTILIZANTES FOSFATADOS

, 2001
JOCELYN LOPES DE SOUZA
openalex   +2 more sources

Mesoscale Recovery of Microglial and Neuronal Dynamics After Craniotomy Across Wide Cortex in Transgenic Mice

Advanced Science, EarlyView.
This study employs longitudinal fluorescence imaging in transgenic mice to map post‐craniotomy cortical recovery. We identify distinct neuroimmune recovery phases: microglial structural inflammation peaks at ∼10 days, neuronal structural intensity peaks at ∼14 days and correlates with microglial activity, and functional network modularity is most ...
Guihua Xiao, Zhilei Wang, Pengchang Zheng, Jingyu Xie, Yangzhen Wang, Yun Chen, Zilin Wang, Ao Li, Minghuan Wang, Quanbo Ji, Can Gao, Di Yao, Lingbo Li, Jiangbei Cao   +13 more
wiley   +1 more source

Comparison of Deep Learning Architectures for Cardiac Contour Segmentation in Catheterization Radiographs. [PDF]

Cureus
Huang KA, Subramanian B, Choudhary HK, Rehman AU, Prakash NS.   +4 more
europepmc   +1 more source