Results 51 to 60 of about 16,532,252 (340)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Evaluation of temperament tests in beef steers

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2005
The aim of the study was to evaluate three times repetited measurements of the beef steers temperament using of the Scale Test (1–5 score from docile to wild) and the Flight Speed Test (the time taken to cover a set distance of 1.7 m after leaving the ...
János Tőzsér   +5 more
doaj   +1 more source

Significance of solar trees: Configuration, operation, types and technology commercialization

open access: yesEnergy Reports, 2022
Developing energy efficiencies solutions from sunlight to electricity is a crucial solution for the world’s energy shortage and reducing greenhouse gas emissions.
Mensour Almadhhachi   +2 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Crystal structure of 2-acetonyl-5-benzyl-4,6-dimethoxy-5-nitro-2,5-dihydropyrimidine, C16H19N3O5

open access: yesZeitschrift für Kristallographie - New Crystal Structures, 2003
C16H19N3O5, monoclinic, P121/c1 (No. 14), a = 12.010(1) Å, b = 11.877(1) Å, c = 12.110(1) Å, β = 95.83(2)°, V = 1718.5 Å3, Z = 4, Rgt(F) = 0.044, wRref(F2) = 0.129, T = 289 K.
Van Meervelt L., Uytterhoeven K.
doaj   +1 more source

Dry sliding wear characteristics of multi-walled carbon nanotubes reinforced Al-Si (LM6) alloy nanocomposites produced by powder metallurgy technique

open access: yesMaterials Research Express, 2020
The present work involved the production of Metal Matrix Composites (MMCs) of Aluminium Silicon (Al-Si) alloy reinforced with Multi Walled Carbon Nano Tubes (MWCNTs) using Powder Metallurgy (PM) process.
Shivaramu H T   +2 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Carcass value of the progeny of tested beef bulls

open access: yesCzech Journal of Animal Science, 2004
In the study focused on the estimation of the efficiency of beef cattle in the conditions of the Czech Republic, 361 half-carcasses of the offspring of crossbred bulls of tested young beef sires were dissected.
P. Polách   +4 more
doaj   +1 more source

Test of lepton universality with B 0 → K *0 ℓ + ℓ − decays [PDF]

open access: yes, 2017
A test of lepton universality, performed by measuring the ratio of the branching fractions of the B 0 → K *0 μ + μ − and B 0 → K *0 e + e − decays, $$ {R}_{K^{*0}} $$ , is presented.
L. C. R. Aaij   +499 more
semanticscholar   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

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