Results 51 to 60 of about 16,532,252 (340)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet +17 morewiley +1 more sourceEvaluation of temperament tests in beef steers
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2005 The aim of the study was to evaluate three times repetited measurements of the beef steers temperament using of the Scale Test (1–5 score from docile to wild) and the Flight Speed Test (the time taken to cover a set distance of 1.7 m after leaving the ...János Tőzsér, Andrea Szentléleki, Rita Zándoki, Katalin Maros, Zoltán Domokos, Jan Kuchtík +5 moredoaj +1 more sourceLDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber +13 morewiley +1 more sourceCrystal structure of 2-acetonyl-5-benzyl-4,6-dimethoxy-5-nitro-2,5-dihydropyrimidine, C16H19N3O5
Zeitschrift für Kristallographie - New Crystal Structures, 2003 C16H19N3O5, monoclinic, P121/c1 (No. 14), a = 12.010(1) Å, b = 11.877(1) Å, c = 12.110(1) Å, β = 95.83(2)°, V = 1718.5 Å3, Z = 4, Rgt(F) = 0.044, wRref(F2) = 0.129, T = 289 K.Van Meervelt L., Uytterhoeven K.doaj +1 more sourceBasroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim +4 morewiley +1 more sourceCarcass value of the progeny of tested beef bulls
Czech Journal of Animal Science, 2004 In the study focused on the estimation of the efficiency of beef cattle in the conditions of the Czech Republic, 361 half-carcasses of the offspring of crossbred bulls of tested young beef sires were dissected.P. Polách, J. Šubrt, M. Bjelka, K. Uttendorfský, R. Filipčík +4 moredoaj +1 more sourceTest of lepton universality with B 0 → K *0 ℓ + ℓ − decays [PDF]
, 2017 A test of lepton universality, performed by measuring the ratio of the branching fractions of the B
0 → K
*0
μ
+
μ
− and B
0 → K
*0
e
+
e
− decays, $$ {R}_{K^{*0}} $$
, is presented.L. C. R. Aaij, B. Adeva, M. Adinolfi, Z. Ajaltouni, S. Akar, J. Albrecht, F. Alessio, M. Alexander, S. Ali, G. Alkhazov, P. Cartelle, A. Alves, S. Amato, S. Amerio, Y. Amhis, L. An, L. Anderlini, G. Andreassi, M. Andreotti, J. Andrews, R. Appleby, F. Archilli, P. d’Argent, J. Romeu, A. Artamonov, M. Artuso, E. Aslanides, G. Auriemma, M. Baalouch, I. Babuschkin, S. Bachmann, J. Back, A. Badalov, C. Baesso, S. Baker, V. Balagura, W. Baldini, A. Baranov, R. Barlow, C. Barschel, S. Barsuk, W. Barter, F. Baryshnikov, M. Baszczyk, V. Batozskaya, V. Battista, A. Bay, L. Beaucourt, J. Beddow, F. Bedeschi, I. Bediaga, A. Beiter, L. Bel, V. Bellee, N. Belloli, K. Belous, I. Belyaev, E. Ben-Haim, G. Bencivenni, S. Benson, S. Beranek, A. Berezhnoy, R. Bernet, D. Berninghoff, A. Bertolin, C. Betancourt, F. Betti, M. Bettler, M. Beuzekom, I. Bezshyiko, S. Bifani, P. Billoir, A. Birnkraut, A. Bitadze, A. Bizzeti, T. Blake, F. Blanc, J. Blouw, S. Blusk, V. Bocci, T. Boettcher, A. Bondar, N. Bondar, W. Bonivento, I. Bordyuzhin, A. Borgheresi, S. Borghi, M. Borisyak, M. Borsato, M. Borysova, F. Bossu, Meriem Boubdir, T. Bowcock, E. Bowen, C. Bozzi, S. Braun, T. Britton, J. Brodzicka, E. Buchanan, C. Burr, A. Bursche, J. Buytaert, W. Byczynski, S. Cadeddu, H. Cai, R. Calabrese, R. Calladine, M. Calvi, M. C. Gomez, A. Camboni, P. Campana, D. C. Pérez, L. Capriotti, A. Carbone, G. Carboni, R. Cardinale, A. Cardini, P. Carniti, L. Carson, K. Akiba, G. Casse, L. Cassina, L. Garcia, M. Cattaneo, G. Cavallero, R. Cenci, D. Chamont, M. Charles, P. Charpentier, G. Chatzikonstantinidis, M. Chefdeville, S. Chen, S. Cheung, V. Chobanova, M. Chrzaszcz, A. Chubykin, X. Vidal, G. Ciezarek, P. Clarke, M. Clemencic, H. Cliff, J. Closier, V. Coco, J. Cogan, E. Cogneras, V. Cogoni, L. Cojocariu, P. Collins, T. Colombo, A. Comerma-Montells, A. Contu, A. Cook, G. Coombs, S. Coquereau, G. Corti, M. Corvo, C. M. Sobral, B. Couturier, G. Cowan, D. Craik, A. Crocombe, M. C. Torres, S. Cunliffe, R. Currie, C. D’Ambrosio, F. Marinho, E. Dall’Occo, J. Dalseno, A. Davis, O. Francisco, K. Bruyn, S. Capua, M. Cian, J. Miranda, L. Paula, M. Serio, P. Simone, C. Dean, D. Decamp, M. Deckenhoff, L. Buono, H. Dembinski, M. Demmer, A. Dendek, D. Derkach, O. Deschamps, F. Dettori, B. Dey, A. Canto, P. Nezza, H. Dijkstra, F. Dordei, M. Dorigo, A. Su'arez, L. Douglas, A. Dovbnya, K. Dreimanis, L. Dufour, G. Dujany, K. Dungs, P. Durante, R. Dzhelyadin, M. Dziewiecki, A. Dziurda, A. Dzyuba, N. D'el'eage, S. Easo, M. Ebert, U. Egede, V. Egorychev, S. Eidelman, S. Eisenhardt, U. Eitschberger, R. Ekelhof, L. Eklund, S. Ely, S. Esen, H. Evans, T. Evans, A. Falabella, N. Farley, S. Farry, R. Fay, D. Fazzini, L. Federici, D. Ferguson, G. Fernández, P. F. Declara, A. F. Prieto, F. Ferrari, F. Rodrigues, M. Ferro-Luzzi, S. Filippov, R. Fini, M. Fiore, M. Fiorini, M. Firlej, C. Fitzpatrick, T. Fiutowski, F. Fleuret, K. Fohl, M. Fontana, F. Fontanelli, D. Forshaw, R. Forty, V. F. Lima, M. Frank, C. Frei, J. Fu, W. Funk, E. Furfaro, C. Farber, E. Gabriel, A. Torreira, D. Galli, S. Gallorini, S. Gambetta, M. Gandelman, P. Gandini, Y. Gao, L. Martin, J. G. Pardiñas, J. G. Ticó, L. Garrido, P. Garsed, D. Gascón, C. Gaspar, L. Gavardi, G. Gazzoni, D. Gerick, E. Gersabeck, M. Gersabeck, T. Gershon, P. Ghez, S. Gianì, V. Gibson, O. Girard, L. Giubega, K. Gizdov, V. Gligorov, D. Golubkov, A. Golutvin, A. Gomes, I. Gorelov, C. Gotti, E. Govorkova, R. Diaz, L. Cardoso, E. Graug'es, E. Graverini, G. Graziani, A. Grecu, R. Greim, P. Griffith, L. Grillo, L. Gruber, B. R. G. Cazon, O. Grunberg, E. Gushchin, Y. Guz, T. Gys, C. Gobel, T. Hadavizadeh, C. Hadjivasiliou, G. Haefeli, C. Haen, S. Haines, B. Hamilton, X. Han, S. Hansmann-Menzemer, N. Harnew, S. Harnew, J. Harrison, M. Hatch, J. He, T. Head, A. Heister, K. Hennessy, P. Henrard, L. Henry, E. Herwijnen, M. Heß, A. Hicheur, D. Hill, P. H. Hopchev, P. Hopchev, Z. Huard, W. Hulsbergen, T. Humair, M. Hushchyn, D. Hutchcroft, M. Idzik, P. Ilten, R. Jacobsson, J. Jalocha, E. Jans, A. Jawahery, F. Jiang, M. John, D. Johnson, C. Jones, C. Joram, B. Jost, N. Jurik, S. Kandybei, M. Karacson, J. Kariuki, S. Karodia, M. Kecke, M. Kelsey, M. Kenzie, T. Ketel, E. Khairullin, B. Khanji, C. Khurewathanakul, T. Kirn, S. Klaver, K. Klimaszewski, T. Klimkovich, S. Koliiev, M. Kolpin, I. Komarov, R. Kopecná, P. Koppenburg, A. Kosmyntseva, S. Kotriakhova, M. Kozeiha, L. Kravchuk, M. Kreps, P. Krokovny, F. Kruse, W. Krzemień, W. Kucewicz, M. Kucharczyk, V. Kudryavtsev, A. Kuonen, K. Kurek, T. Kvaratskheliya, D. Lacarrere, G. Lafferty, A. Lai, G. Lanfranchi, C. Langenbruch, T. Latham, C. Lazzeroni, R. Gac, J. Leerdam, A. Leflat, J. Lefranccois, R. Lefèvre, F. Lemaitre, E. Cid, O. Leroy, T. Lesiak, B. Leverington, T. Li, Y. Li, Z. Li, Tatiana Likhomanenko, R. Lindner, F. Lionetto, X. Liu, D. Loh, I. Longstaff, J. Lopes, D. Lucchesi, M. Martinez, H. Luo, A. Lupato, E. Luppi, O. Lupton, A. Lusiani, X. Lyu, F. Machefert, F. Maciuc, B. Maddock, O. Maev, K. Maguire, S. Malde, A. Malinin, T. Maltsev, G. Manca, G. Mancinelli, P. Manning, D. Marangotto, J. Maratas, J. Marchand, U. Marconi, C. Benito, M. Marinangeli, P. Marino, J. Marks, G. Martellotti, M. Martin, M. Martinelli, D. M. Santos, F. Vidal, D. M. Tostes, L. Massacrier, A. Massafferri, R. Matev, A. Mathad, Z. Máthé, C. Matteuzzi, A. Mauri, E. Maurice, B. Maurin, A. Mazurov, M. McCann, A. McNab, R. McNulty, B. Meadows, F. Meier, D. Melnychuk, M. Merk, A. Merli, E. Michielin, D. Milanes, M. Minard, D. Mitzel, A. Mogini, J. M. Rodriguez, I. A. Monroy, S. Monteil, M. Morandin, M. Morello, O. Morgunova, J. Moroń, A. Morris, R. Mountain, F. Muheim, M. Mulder, M. Mussini, D. Muller, J. Muller, K. Muller, V. Muller, P. Naik, T. Nakada, R. Nandakumar, A. Nandi, I. Nasteva, M. Needham, N. Neri, S. Neubert, N. Neufeld, M. Neuner, T. Nguyen, C. Nguyen-Mau, S. Nieswand, R. Niet, N. Nikitin, T. Nikodem, A. Nogay, D. O’Hanlon, A. Oblakowska-Mucha, V. Obraztsov, S. Ogilvy, R. Oldeman, C. Onderwater +499 moresemanticscholar +1 more sourceUnderstanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak +8 morewiley +1 more source