Results 51 to 60 of about 26,603,463 (326)

Disturbances of metabolic homeostasis is liver disease.

open access: yesActa Médica Portuguesa, 1981
The liver occupies a major role in metabolic homeostasis with important functions in carbohydrate, fat and protein metabolism. Abnormalities in glucose homeostasis are common in all forms of liver disease although fasting hypoglycaemia is surprisingly ...
K. G. M. M. Alberti   +3 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Traffic noise measurements in antwerp and brussels and their relation with annoyance

open access: yesArchives of Acoustics, 2016
This work is a part of a large scale traffic noise survey in two Belgian cities: Antwerp and Brussels. A social survey (interviews of 1800 persons) was coupled with intensive acoustical measurements (40 places in Antwerp and 25 in Brussels, covering ...
H. MYNCKE   +3 more
doaj  

Influence of the diet on the morphology of ruminal and intestinal mucosa and on intestinal carbohydrase levels in cattle

open access: yesVeterinární Medicína, 2003
This study examined the effects of extensive and intensive feeding on the morphology of the gastrointestinal tract as well as on the level of carbohydrase activity in the small intestine of growing cattle.
R. Zitnan   +8 more
doaj   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Evaluation of temperament tests in beef steers

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2005
The aim of the study was to evaluate three times repetited measurements of the beef steers temperament using of the Scale Test (1–5 score from docile to wild) and the Flight Speed Test (the time taken to cover a set distance of 1.7 m after leaving the ...
János Tőzsér   +5 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Crystal structure of 2-acetonyl-5-benzyl-4,6-dimethoxy-5-nitro-2,5-dihydropyrimidine, C16H19N3O5

open access: yesZeitschrift für Kristallographie - New Crystal Structures, 2003
C16H19N3O5, monoclinic, P121/c1 (No. 14), a = 12.010(1) Å, b = 11.877(1) Å, c = 12.110(1) Å, β = 95.83(2)°, V = 1718.5 Å3, Z = 4, Rgt(F) = 0.044, wRref(F2) = 0.129, T = 289 K.
Van Meervelt L., Uytterhoeven K.
doaj   +1 more source

Dry sliding wear characteristics of multi-walled carbon nanotubes reinforced Al-Si (LM6) alloy nanocomposites produced by powder metallurgy technique

open access: yesMaterials Research Express, 2020
The present work involved the production of Metal Matrix Composites (MMCs) of Aluminium Silicon (Al-Si) alloy reinforced with Multi Walled Carbon Nano Tubes (MWCNTs) using Powder Metallurgy (PM) process.
Shivaramu H T   +2 more
doaj   +1 more source

Significance of solar trees: Configuration, operation, types and technology commercialization

open access: yesEnergy Reports, 2022
Developing energy efficiencies solutions from sunlight to electricity is a crucial solution for the world’s energy shortage and reducing greenhouse gas emissions.
Mensour Almadhhachi   +2 more
doaj   +1 more source

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