Results 111 to 120 of about 15,754,334 (318)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
مجلة النهرين للعلوم الهندسيةThis paper discusses the development of a seven-band coherent wavelength-division multiplexing (WDM) system covering the T to U systems, aiming to enhance the capacity and system efficiency. Seven multiband systems (C+L, S+C+L, S+C+L+U, E+S+C+L, E+S+C+L+
Arwa A. Moosa, Raad Sami Fyath
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Insight into the nature of the $$P_{c}(4457)$$ P c ( 4457 ) and related pentaquarks
European Physical Journal C: Particles and FieldsWe systematically study the electromagnetic properties of pentaquark states from different perspectives to better understand their nature, internal structure, and quantum numbers, determine their hadronization processes, and shed light on their true ...
Ulaş ÖZDEM
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FEBS Open Bio, EarlyView.This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart +4 more
wiley +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
On the capacity of multi-antenna Gaussian channels
Proceedings. 2001 IEEE International Symposium on Information Theory (IEEE Cat. No.01CH37252), 2001 N. Chiurtu, B. Rimoldi, E. Telatar
semanticscholar +1 more source
HaematologicaBackground: Myelodysplastic neoplasms (MDS) with deletion 5q (del5q) are characterized by red blood cell transfusion dependence (RBC-TD and about one third of patients are refractory/resistant/ineligible to lenalidomide.
E.N. Oliva +22 more
doaj
Zhejiang Daxue xuebao. Lixue banIn this paper, we firstly establish an global bifurcation result for the problems involving jumping non-linearities with mean curvature operator in Minkowski space.
沈文国(SHEN Wenguo)
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