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Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source

Existence and uniqueness of solutions for multi-order fractional differential equations with integral boundary conditions

Boundary Value Problems
In this paper, we consider the existence and uniqueness of solutions for the following nonlinear multi-order fractional differential equation with integral boundary conditions { ( C D 0 + α u ) ( t ) + ∑ i = 1 m λ i ( t ) ( C D 0 + α i u ) ( t ) + ∑ j ...
Jian-Ping Sun, Li Fang, Ya-Hong Zhao, Qian Ding +3 more
doaj +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source

E X P R E S I Ó N D E L O S G E N E S H D L - B G B P , α - G L U C O S I D A S A y α - A M I L A S A E N E L H E P A T O P A N C R E A S D E C A M A R O N B L A N C O P e n a e u s ( L i t o p e n a e u s v a n n a m e i ) E N R E S P U E S T A A L A I N O C U L A C I Ó N D E G L U C A N O S

, 2003
Los camarones utilizan enzimas digestivas para la hidrólisis de proteínas, lipidos y polímeros de carbohidratos, presentes tanto en alimentos naturales o dietas preparadas. Entre las glicohidrolasas encontradas en camarones se encuentran las α-amilasas, α-glucosidasas y quitinasas.
openaire +3 more sources

Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting +12 more
wiley +1 more source

Normalized solutions to nonlinear Schrödinger equations with mixed fractional Laplacians

Advances in Nonlinear Analysis
We consider the following elliptic problem with mixed local and nonlocal operators: (−Δ)s1u+(−Δ)s2u+λu=f(u)inRN,∫RN∣u(x)∣2dx=c,u∈Hs2(RN),\left\{\begin{array}{l}{\left(-\Delta )}^{{s}_{1}}u+{\left(-\Delta )}^{{s}_{2}}u+\lambda u=f\left(u)\hspace{1.0em ...
Mao Anmin, Yan Changchang
doaj +1 more source

Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster +11 more
wiley +1 more source

A Comprehensive Overview of the Clinical, Electrophysiological, and Neuroimaging Features of BPAN: Insights From a New Case Series

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Neurodegeneration with brain iron accumulation (NBIA) comprises a genetically and clinically heterogeneous group of rare neurological disorders characterized particularly by iron accumulation in the basal ganglia. To date, 15 genes have been associated with NBIA.
Seda Susgun +95 more
wiley +1 more source

The ALICE experiment at the CERN LHC

, 2003
K. Aamodt +499 more
semanticscholar +1 more source

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic +6 more
wiley +1 more source

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