Results 121 to 130 of about 147,425 (281)
Journal of Materials Research and TechnologyNickel-based superalloys are crucial in aerospace applications, but they are challenging to machine due to their high cutting forces and severe tool wear.
Shenghao Chao +5 more
doaj +1 more source
Evaluating the optimal duration of medication treatment for opioid use disorder
Addiction, EarlyView.Abstract Background and aims Clinicians have little guidance on the ideal length of time patients should remain on medication treatment for opioid use disorder (MOUD) before being able to safely discontinue MOUD. This study estimated how the risk of all‐cause mortality changes with the duration of MOUD, controlling for patient characteristics that ...
Corey J. Hayes +5 more
wiley +1 more source
Dendrimeric Antigens for Passive Mast Cell Activation in the Evaluation of Amoxicillin Allergy
Allergy, EarlyView.DeAns with defined nanoscale structure reveal that conjugate size and determinant density govern IgE‐mediated effector‐cell activation in AX allergy. All DeAn generations bind to sIgE in inhibition immunoassay, but only larger DeAns trigger FcεRI‐dependent responses in mouse MC, huRBL‐2H3, and LUVA cells.
Amene Tesfaye Ayane +12 more
wiley +1 more source
Scientific ReportsCurrently, in vitro cultured corneal epithelial transplantation is effective in treating limbal stem cell dysfunction (LSCD). Selecting carriers is crucial for constructing the corneal epithelium through tissue engineering. In this study, the traditional
Qiurong Long +8 more
doaj +1 more source
Acta Ophthalmologica, EarlyView.Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry +27 more
wiley +1 more source
The Synthesis of Symbolism, Romantism and Existentialism in the short-story “The Senior Boyar” by Todos Osmachka [PDF]
, 2008 Стаття продовжує цикл публікацій автора про МУР (Мистецький український рух). Проаналізовано тенденції, пов’язані з синтезом традиційних реалістичних моделей (трьох способів узагальнення дійсності – ідеалізації, символізації та типізації) із ...
Lysenko-Kovalova, Nataliia +1 more
core
Multimodal TransportationUrban Air Mobility (UAM) is poised to revolutionize transportation, necessitating an assessment of public acceptance before broad commercial adoption. This study presents the Urban Air Mobility Acceptance Model (UAM-AM), which draws from the Technology ...
Enjian Yao +3 more
doaj +1 more source
Neuronal hyperexcitability: A key to unraveling hippocampal synaptic dysfunction in Lafora disease
Epilepsia, EarlyView.Abstract Background and Objective Lafora disease (LD) is a rare progressive disorder caused by mutations in the EPM2A or EPM2B genes, characterized by the accumulation of Lafora bodies, drug‐resistant epilepsy, and cognitive decline. To investigate the early molecular mechanisms of LD, we studied electrophysiological changes in the dentate gyrus (DG ...
Cinzia Costa +17 more
wiley +1 more source
The FEBS Journal, EarlyView.Moderate overexpression of wild‐type Met in hepatocytes (Alb‐R26Met mouse model) boosts a strong antioxidant response dependent on the glutathione system while impairing TGF‐β signaling in the liver. This leads to improved liver regeneration and protects against DDC‐induced injury, a model for cholestatic disease sharing features with primary ...
Carlos González‐Corralejo +16 more
wiley +1 more source
Sustainable FuturesUrban Air Mobility (UAM) is an emerging trend in global transportation, with expectations for large-scale expansion in the near future. However, the widespread implementation of passenger drones requires further analysis, particularly regarding user ...
Fitri Trapsilawati +5 more
doaj +1 more source