Results 31 to 40 of about 42,127 (265)
USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis
Advanced Science, EarlyView.This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui +5 more
wiley +1 more source
Advanced Science, EarlyView.In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun +15 more
wiley +1 more source
Studia i Materiały, 2017 This paper applies various theories of firms to explain existence of sharing economies platforms based on Uber examples. The purpose of this article is to investigate if existing theories like: transaction costs theory, resource based view, theory of ...
Tomasz Meksuła
doaj +1 more source
Data-Centric Engineering, 2021 Monte Carlo algorithms simulates some prescribed number of samples, taking some random real time to complete the computations necessary. This work considers the converse: to impose a real-time budget on the computation, which results in the number of ...
Lawrence M. Murray +2 more
doaj +1 more source
Growth of Omnichannel Grocery Retailing and Food Prices
Agribusiness, EarlyView.ABSTRACT This paper examines the effects of the growth of omnichannel grocery retailing on food prices. We first develop a conceptual model of consumer choice and retailer pricing that allows us to evaluate changes in equilibrium prices, quantities, and profits with online channel growth and alternative pricing strategies.
Xiangwen Kong +2 more
wiley +1 more source
“UBER SKOLIOSIS ISCHIADICA” [PDF]
The Journal of Nervous and Mental Disease, 1900 n ...
openaire +2 more sources
Australian Journal of Social Issues, EarlyView.ABSTRACT Migrant healthcare workers in Australia find themselves at the centre of three intersecting concerns, often presented as ‘crises’ in contemporary discourse: the ‘care crisis’, the ‘housing crisis’ and the ‘migration crisis.’ Yet their own perspectives on these issues are rarely foregrounded. This paper explores the role of homeownership in the
Leah Williams Veazey
wiley +1 more source
Zähmung eines blauen Gases—Struktur und Chemie von Hexafluorthioaceton
Angewandte Chemie, EarlyView.Hexaflouorthioaceton (1), ein blaues Gas bei Raumtemperatur, wurde durch Vakuumpyrolyse des zyklischen Dimers bei 660 °C synthetisiert. Wir diskutieren grundlegende Eigeschaften des schwer greifbaren 1, einschließlich Einkristallstruktur und Kernmagnetische Resonansspektroskopie, obwohl es eine starke Tendenz zur Dimerisierung selbst bei –74 °C zeigt ...
Hennes Günther +3 more
wiley +1 more source
Synthese Unkonventioneller α‐Polyhalogenierter Amine Durch Hydroaminoalkylierung
Angewandte Chemie, EarlyView.Es wird ein redox‐neutrales Verfahren beschrieben, bei dem Alkene und Alkine unter Verwendung stabiler Hemiaminal‐Reagenzien in α‐Polyhalogenmethylamine umgewandelt werden. Dieser Ansatz ermöglicht den Zugang zu α‐CF3‐, α‐CF2H‐, α‐CF2Cl‐, und α‐CFClH‐Aminen und besticht durch ein breites Substratspektrum, eine hohe Toleranz gegenüber funktionellen ...
Angela K. Hofmeister +9 more
wiley +1 more source
A plataforma Uber e o mercado de automóveis no Brasil
Economia & Região, 2023 O presente estudo teve como objetivo analisar o comportamento da demanda brasileira de automóveis a partir da entrada da plataforma Uber no mercado, considerando variáveis microeconômicas, macroeconômicas, crédito e a Plataforma Uber. O método utilizado
Pedro Augusto Lopes Soyer +1 more
doaj +1 more source